Usage of Multimodal Evoked Potentials in Diagnosis of Central Nervous System Changes in Multiple Sclerosis

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dc.contributor.authorOzbek, Bahar
dc.contributor.authorBalci, Kemal
dc.contributor.authorCelik, Yahya
dc.date.accessioned2024-06-12T11:08:49Z
dc.date.available2024-06-12T11:08:49Z
dc.date.issued2011
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: Evoked potentials are used in the functional assessment of sensory and motor pathways. Conflicting results have been reported in different studies about the value of evoked potentials in demyelinating diseases. Over 80% of patients with multiple sclerosis present with a relapsing-remitting form of the disease. In this study, we aimed to examine the value of each evoked potential in demonstrating the demyelinating lesions in a homogeneous group of patients with relapsing-remitting multiple sclerosis. We also aimed to examine the correlation between clinical status and evoked potential abnormalities. Patients and Methods: Twenty patients with relapsing-remitting multiple sclerosis, and 10 healthy volunteers were included in the study to evaluate the value of evoked potentials in a homogeneous group. Visual, somatosensory and motor evoked potentials (VEP, SEP, MEP) were measured and the Expanded Disability Status Scale (EDSS) scores of the patients were calculated. Results: Of 20 patients, 15 (75%) had VEP abnormality, 14 (70%) had MEP abnormality and 12 (60%) had tibial SEP abnormality. All patients had at least one abnormal evoked potential measurement. Abnormality of evoked potentials was also correlated with high EDSS scores. Conclusion: We concluded that evoked potentials, especially used in combination, are good markers to show nerve damage damage in patients with multiple sclerosis.en_US
dc.identifier.endpage44en_US
dc.identifier.issn1301-062X
dc.identifier.issn1309-2545
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-79957597682en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage38en_US
dc.identifier.trdizinid128114en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/128114
dc.identifier.urihttps://hdl.handle.net/20.500.14551/22578
dc.identifier.volume17en_US
dc.identifier.wosWOS:000217521400005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTurkish Neurological Socen_US
dc.relation.ispartofTurkish Journal Of Neurologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectMultiple Sclerosisen_US
dc.subjectRelapsing-Remittingen_US
dc.subjectEvoked Potentialsen_US
dc.titleUsage of Multimodal Evoked Potentials in Diagnosis of Central Nervous System Changes in Multiple Sclerosisen_US
dc.typeArticleen_US

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