Usage of Multimodal Evoked Potentials in Diagnosis of Central Nervous System Changes in Multiple Sclerosis
Küçük Resim Yok
Tarih
2011
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish Neurological Soc
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: Evoked potentials are used in the functional assessment of sensory and motor pathways. Conflicting results have been reported in different studies about the value of evoked potentials in demyelinating diseases. Over 80% of patients with multiple sclerosis present with a relapsing-remitting form of the disease. In this study, we aimed to examine the value of each evoked potential in demonstrating the demyelinating lesions in a homogeneous group of patients with relapsing-remitting multiple sclerosis. We also aimed to examine the correlation between clinical status and evoked potential abnormalities. Patients and Methods: Twenty patients with relapsing-remitting multiple sclerosis, and 10 healthy volunteers were included in the study to evaluate the value of evoked potentials in a homogeneous group. Visual, somatosensory and motor evoked potentials (VEP, SEP, MEP) were measured and the Expanded Disability Status Scale (EDSS) scores of the patients were calculated. Results: Of 20 patients, 15 (75%) had VEP abnormality, 14 (70%) had MEP abnormality and 12 (60%) had tibial SEP abnormality. All patients had at least one abnormal evoked potential measurement. Abnormality of evoked potentials was also correlated with high EDSS scores. Conclusion: We concluded that evoked potentials, especially used in combination, are good markers to show nerve damage damage in patients with multiple sclerosis.
Açıklama
Anahtar Kelimeler
Multiple Sclerosis, Relapsing-Remitting, Evoked Potentials
Kaynak
Turkish Journal Of Neurology
WoS Q Değeri
N/A
Scopus Q Değeri
Q4
Cilt
17
Sayı
1
