Investigation of the Relationship Between Ischemic Stroke Disease and Serum Zinc Levels

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dc.authoridKEHAYA, Sezgin/0000-0002-9608-9278
dc.authoridKEHAYA, Sezgin/0000-0002-9608-9278
dc.authorwosidKEHAYA, Sezgin/GVU-6069-2022
dc.authorwosidAlkanli, Nevra/D-4400-2019
dc.authorwosidKEHAYA, Sezgin/N-9995-2017
dc.contributor.authorAlkanli, Nevra
dc.contributor.authorAy, Arzu
dc.contributor.authorKehaya, Sezgin
dc.date.accessioned2024-06-12T10:52:47Z
dc.date.available2024-06-12T10:52:47Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: The purpose of this study was to investigate the relationship between the development of ischemic stroke disease and the serum zinc level. Materials and Methods: A total of 22 ischemic stroke patients and 38 healthy controls were included in the study. Routine blood samples of both groups were centrifuged at 5000 rpm for 5 minutes and serum samples were separated from the blood. Distilled water was added to the serum samples to make a total volume of 4 mL. Vortexing was used to homogenize the total mixture and standard solutions were used to detect zinc with an atomic absorption spectrophotometer. A concentration calibration graph was created to illustrate the results. Results: The serum zinc level was significantly higher in the patient group than in the control group (p<0.05). No statistically significant relationship was determined between the serum zinc level and parameters associated with ischemic stroke risk factors and patient complications (p>0.05). However, a strong positive significant correlation was detected between hemoglobin and hematocrit parameters (r=0.936; p<0.001), a moderately positive significant correlation between C-reactive protein and chlorine parameters (r=0.445; p=0.038), a moderately positive significant correlation between sodium and chlorine parameters (r=0.522; p=0.013), and a moderately positive significant correlation between ischemic stroke duration and potassium parameters (r=0.483; p=0.023). Conclusion: The significant increase in the serum zinc level of ischemic stroke patients and the significant positive correlations in parameters associated with ischemic stroke risk factors and complications may indicate an effect on neuronal metabolism that contributes to the development of ischemic stroke.en_US
dc.identifier.doi10.14744/etd.2021.35589
dc.identifier.endpage199en_US
dc.identifier.issn2149-2247
dc.identifier.issn2149-2549
dc.identifier.issue2en_US
dc.identifier.startpage194en_US
dc.identifier.trdizinid530735en_US
dc.identifier.urihttps://doi.org/10.14744/etd.2021.35589
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/530735
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18832
dc.identifier.volume44en_US
dc.identifier.wosWOS:000774517900013en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherErciyes Univ Sch Medicineen_US
dc.relation.ispartofErciyes Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtomic Absorption Spectrophotometeren_US
dc.subjectIschemic Strokeen_US
dc.subjectNeurodegenerative Diseasesen_US
dc.subjectTrace Elementsen_US
dc.subjectZinc Levelen_US
dc.titleInvestigation of the Relationship Between Ischemic Stroke Disease and Serum Zinc Levelsen_US
dc.typeArticleen_US

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