Investigation of the Relationship Between Ischemic Stroke Disease and Serum Zinc Levels
Küçük Resim Yok
Tarih
2022
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Erciyes Univ Sch Medicine
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: The purpose of this study was to investigate the relationship between the development of ischemic stroke disease and the serum zinc level. Materials and Methods: A total of 22 ischemic stroke patients and 38 healthy controls were included in the study. Routine blood samples of both groups were centrifuged at 5000 rpm for 5 minutes and serum samples were separated from the blood. Distilled water was added to the serum samples to make a total volume of 4 mL. Vortexing was used to homogenize the total mixture and standard solutions were used to detect zinc with an atomic absorption spectrophotometer. A concentration calibration graph was created to illustrate the results. Results: The serum zinc level was significantly higher in the patient group than in the control group (p<0.05). No statistically significant relationship was determined between the serum zinc level and parameters associated with ischemic stroke risk factors and patient complications (p>0.05). However, a strong positive significant correlation was detected between hemoglobin and hematocrit parameters (r=0.936; p<0.001), a moderately positive significant correlation between C-reactive protein and chlorine parameters (r=0.445; p=0.038), a moderately positive significant correlation between sodium and chlorine parameters (r=0.522; p=0.013), and a moderately positive significant correlation between ischemic stroke duration and potassium parameters (r=0.483; p=0.023). Conclusion: The significant increase in the serum zinc level of ischemic stroke patients and the significant positive correlations in parameters associated with ischemic stroke risk factors and complications may indicate an effect on neuronal metabolism that contributes to the development of ischemic stroke.
Açıklama
Anahtar Kelimeler
Atomic Absorption Spectrophotometer, Ischemic Stroke, Neurodegenerative Diseases, Trace Elements, Zinc Level
Kaynak
Erciyes Medical Journal
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
44
Sayı
2
