The evaluation of vitamin K status in children with febrile seizure

Basit Öğe Kaydı
dc.contributor.authorCarman, Kürşat Bora
dc.contributor.authorKaral, Yasemin
dc.contributor.authorMert, Gülen Gül
dc.contributor.authorEkici, Arzu
dc.contributor.authorPerk, Pelen
dc.contributor.authorYarar, Çoşkun
dc.contributor.authorDinleyici, Ener Çağrı
dc.date.accessioned2021-11-20T10:10:08Z
dc.date.available2021-11-20T10:10:08Z
dc.date.issued2021
dc.departmentFakülteler, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Çocuk Sağlığı ve Hastalıkları Anabilim Dalıen_US
dc.description.abstractBackground: Febrile seizure is the most common neurological disorder in childhood. The exact pathophysiology of febrile seizures is unknown. Recent studies showed the role of vitamin K in nonhematological and inflammatory disorders. This study aimed to investigate the serum vitamin K levels in children with febrile seizures. Aims: To evaluate vitamin K levels in children with febrile seizures. Study Design: Prospective case-control study. Methods: This multicenter study examined representative populations in 8 different cities in Turkey between April 1, 2018 and April 1, 2019. Blood samples were taken from all children at presentation. Vitamin K1, vitamin K2, tumor necrosis factor-alpha, interleukin 1 beta, and interleukin 6 levels were determined by enzyme-linked immunosorbent assay. Results: A total of 155 children were included in the study—84 children with febrile seizures and 71 children in febrile control group. Serum vitamin K1 and vitamin K2 levels were also higher in children with febrile seizures than in the controls. The results of statistical analysis showed that vitamin K1 and vitamin K2 levels were correlated with tumor necrosis factor-alpha, interleukin 1 beta, and interleukin 6 levels. The median vitamin K1 and vitamin K2 levels of children experiencing their first febrile seizure were higher than those in children with recurrent febrile seizures. Type of febrile seizure has no effect on serum vitamin K1 and vitamin K2 levels. Conclusion: In children with febrile seizures, vitamin K levels are higher than those in the control group. These new findings may contribute to elucidating the etiopathogenesis of febrile seizures.en_US
dc.identifier.doi10.4274/balkanmedj.galenos.2020.2020.5.70en_US
dc.identifier.endpage120en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue2en_US
dc.identifier.pmid33045823en_US
dc.identifier.scopus2-s2.0-85103227447en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage116en_US
dc.identifier.trdizinid411570en_US
dc.identifier.urihttps://doi.org/10.4274/balkanmedj.galenos.2020.2020.5.70
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TkRFeE5UY3dNQT09
dc.identifier.urihttps://hdl.handle.net/20.500.14551/5534
dc.identifier.volume38en_US
dc.identifier.wosWOS:000630173000008en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240608_ID_Qen_US
dc.subject[No Keywords]en_US
dc.titleThe evaluation of vitamin K status in children with febrile seizureen_US
dc.typeArticleen_US

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
5534.pdf
Boyut:
312.25 KB
Biçim:
Adobe Portable Document Format
Açıklama:
Tam Metin / Full Text
İndir

Koleksiyon

TR-Dizin İndeksli Yayınlar Koleksiyonu
Balkan Medical Journal
Makale Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
WoS İndeksli Yayınlar Koleksiyonu