Risk factors for early mortality and morbidity after pneumonectomy

Küçük Resim Yok

Tarih

2014

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Baycinar Medical Publ-Baycinar Tibbi Yayincilik

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

Background: This study aims to investigate possible risk factors which affect the mortality and morbidity of pneumonectomy patients due to the non-small cell lung cancer (NSCLC). Methods: Demographic, clinical and pathological features of 100 patients (96 males, 4 females; mean age 58.4 +/- 8.9 years; range 38 to 82 years) who underwent pneumonectomy between April 2008 and October 2009 were retrospectively analyzed. Results: The morbidity and mortality rates were found to be 56% and 14%, respectively. The complications included cardiopulmonary in 46%, bleeding in 7%, and wound infection in 3% patients. There was no significant effect of age, sex, smoking habit, diabetes, hypertension, and coronary artery disease on 30-day morbidity and mortality. Neoadjuvant therapy (p=0.049), right pneumonectomy (p=0.01), and intraoperative blood transfusion (p=0.049) were associated with significantly increased morbidity. The duration of intensive care unit and hospital stays was significantly longer in patients with respiratory failure and bronchopleural fistula. Conclusion: Pneumonectomy is a high-risk procedure in patients with neoadjuvant therapy, right pneumonectomy, and intraoperative blood transfusion. However, we believe that it is possible to reduce the risk factors with careful preoperative evaluation, rigorous anesthetic assessment and surgical interventions.

Açıklama

Anahtar Kelimeler

Morbidity, Mortality, Pneumonectomy, Cell Lung-Cancer, Randomized Controlled-Trial, Completion Pneumonectomy, Operative Mortality, Complications, Chemotherapy, Radiotherapy, Resection, Surgery, Therapy

Kaynak

Turk Gogus Kalp Damar Cerrahisi Dergisi-Turkish Journal Of Thoracic And Cardiovascular Surgery

WoS Q Değeri

Q4

Scopus Q Değeri

Q3

Cilt

22

Sayı

2

Künye