Relationship between SIRI, SII values, and Alvarado score with complications of acute appendicitis during the COVID-19 pandemic

dc.authorwosidDemirel, Tugrul/JAC-3486-2023
dc.contributor.authorCakcak, Ibrahim Ethem
dc.contributor.authorTurkyilmaz, Zeliha
dc.contributor.authorDemirel, Tugrul
dc.date.accessioned2024-06-12T10:51:06Z
dc.date.available2024-06-12T10:51:06Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBACKGROUND: The aim of the study was to investigate the clinical variations of Systemic Inflammatory Response Index (SIRI), Systemic Inflammation Index (SII), and Alvarado Score during the COVID-19 pandemic period. METHODS: Between March 2019 and March 2021, 161 consecutive patients who had surgery due to acute appendicitis were retrospectively recruited from Trakya University in Edirne, Turkey. Group I included patients who had surgery during the COVID-19 pandemic and Group II included patients who had surgery before the COVID-19 pandemic period. A total of 80 patients volunteered for Group I and 81 patients for Group II. The neutrophil/lymphocyte ratio (NLR), platelet/lymphocyte ratio, and lymphocyte/monocyte ratio were calculated. SII was calculated by the formula: platelet (P) x neutrophil (N)/lymphocyte (L). NLR was calculated by dividing the neutrophil count by the number of lymphocytes. SIRI was defined as follows: SIRI = (neutrophil x monocyte/lymphocyte). The Alvarado score was also calculated by using patient history, clinical examination, and laboratory findings. RESULTS: There was a significant difference between the two groups in terms of displacing pain, nausea/vomiting, right lower quadrant tenderness, rebound, hyperthermia, leukocytosis, and total Alvarado score (p<0.001). There was a significant difference between two groups in comparison of C-reactive protein, SIRI, and SII values (p<0.001). Group I patients had higher values of these parameters than Group II. CONCLUSION: Based on the results obtained from this study, we conclude that COVID-19 pandemic has caused an increase in patients with acute appendicitis admitted to the hospital. This late diagnosis of acute appendicitis caused more complications during COVID-19 pandemic. Alvarado score, SIRI, and SII can be used as a marker to indicate whether complications of acute appendicitis occurred pre-or post-operatively. Therefore, Alvarado score, SIRI, and SII are directly proportional to the complication of acute appendicitis.en_US
dc.identifier.doi10.14744/tjtes.2021.94580
dc.identifier.endpage755en_US
dc.identifier.issn1306-696X
dc.identifier.issn1307-7945
dc.identifier.issue6en_US
dc.identifier.pmid35652883en_US
dc.identifier.scopus2-s2.0-85131265619en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage751en_US
dc.identifier.trdizinid1138201en_US
dc.identifier.urihttps://doi.org/10.14744/tjtes.2021.94580
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1138201
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18244
dc.identifier.volume28en_US
dc.identifier.wosWOS:000809604900006en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Assoc Trauma Emergency Surgeryen_US
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal Of Trauma & Emergency Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAkut Appendicitisen_US
dc.subjectAlvaradoen_US
dc.subjectCOVID-19en_US
dc.subjectSIIen_US
dc.subjectSIRIen_US
dc.subjectImmune-Inflammation Indexen_US
dc.subjectRenal-Cell Carcinomaen_US
dc.subjectPrognostic Valueen_US
dc.subjectDiagnosisen_US
dc.subjectSurvivalen_US
dc.titleRelationship between SIRI, SII values, and Alvarado score with complications of acute appendicitis during the COVID-19 pandemicen_US
dc.typeArticleen_US

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