The epidemiology of antineutrophil cytoplasmic antibody-associated vasculitis in northwestern Turkey

dc.contributor.authorPamuk, Omer Nuri
dc.contributor.authorDonmez, Salim
dc.contributor.authorCalayir, Gokce Busra
dc.contributor.authorPamuk, Gulsum Emel
dc.date.accessioned2024-06-12T10:52:02Z
dc.date.available2024-06-12T10:52:02Z
dc.date.issued2016
dc.departmentTrakya Üniversitesien_US
dc.description.abstractEpidemiological data about antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is very limited. Until now, there has been no study about the epidemiology of AAV in Turkey. In this study, we evaluated the frequency of AAV in the northeastern part of Turkey. The general clinical features of patients diagnosed with AAV at our center within the last 10 years (2004-2014) were retrospectively recorded down. The incidence rates and the prevalence per 1,000,000 population aged a parts per thousand yen16 years were calculated. In addition, we evaluated the clinical features and survival rates of AAV patients. There were 30 patients with granulomatous polyangiitis (GPA), 15 with microscopic polyangiitis (MPA), and 5 with eosinophilic polyangiitis (EGPA). The overall prevalence of AAV in our region was 69.3/1,000,000 in individuals a parts per thousand yen16 years. Males had a similar prevalence (73.2/1,000,000) with females (65.4/1,000,000). The mean annual incidence rate was 8.1/million for all AAV. The annual incidence of AAV in females was 6.9/million; in males, it was 9.2/million. The annual incidence for GPA was calculated as 4.8/1,000,000, the incidence for MPA was 2.4/1,000,000, and the incidence for CSS was 0.8/1,000,000. Ten-year survival of patients with AAV was 65.3 %. The only independent poor prognostic factor in Cox's multivariate analysis was advanced age at the time of diagnosis (OR 7.5, 95 % CI 10.6-526, p = 0.043). The frequency of all AAV in northwestern Turkey was similar to that in southern Europe; however, it was lower than the frequency in Northern Europe.en_US
dc.identifier.doi10.1007/s10067-016-3232-y
dc.identifier.endpage2071en_US
dc.identifier.issn0770-3198
dc.identifier.issn1434-9949
dc.identifier.issue8en_US
dc.identifier.pmid26992904en_US
dc.identifier.scopus2-s2.0-84961233706en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage2063en_US
dc.identifier.urihttps://doi.org/10.1007/s10067-016-3232-y
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18574
dc.identifier.volume35en_US
dc.identifier.wosWOS:000380265100023en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSpringer London Ltden_US
dc.relation.ispartofClinical Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAntineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV)en_US
dc.subjectEosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) (EGPA)en_US
dc.subjectEpidemiologyen_US
dc.subjectGranulatomatosis With Polyangiitis (Wegener) (GPA)en_US
dc.subjectMicroscopic Polyangiitis (MPA)en_US
dc.subjectPrimary Systemic Vasculitidesen_US
dc.subjectChurg-Strauss-Syndromeen_US
dc.subjectRheumatology 1990 Criteriaen_US
dc.subjectGiant-Cell Arteritisen_US
dc.subjectWegeners-Granulomatosisen_US
dc.subjectMicroscopic Polyangiitisen_US
dc.subjectPolyarteritis-Nodosaen_US
dc.subjectConsensus Conferenceen_US
dc.subjectClassificationen_US
dc.subjectPopulationen_US
dc.titleThe epidemiology of antineutrophil cytoplasmic antibody-associated vasculitis in northwestern Turkeyen_US
dc.typeArticleen_US

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