The epidemiology of antineutrophil cytoplasmic antibody-associated vasculitis in northwestern Turkey
Küçük Resim Yok
Tarih
2016
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Springer London Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Epidemiological data about antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV) is very limited. Until now, there has been no study about the epidemiology of AAV in Turkey. In this study, we evaluated the frequency of AAV in the northeastern part of Turkey. The general clinical features of patients diagnosed with AAV at our center within the last 10 years (2004-2014) were retrospectively recorded down. The incidence rates and the prevalence per 1,000,000 population aged a parts per thousand yen16 years were calculated. In addition, we evaluated the clinical features and survival rates of AAV patients. There were 30 patients with granulomatous polyangiitis (GPA), 15 with microscopic polyangiitis (MPA), and 5 with eosinophilic polyangiitis (EGPA). The overall prevalence of AAV in our region was 69.3/1,000,000 in individuals a parts per thousand yen16 years. Males had a similar prevalence (73.2/1,000,000) with females (65.4/1,000,000). The mean annual incidence rate was 8.1/million for all AAV. The annual incidence of AAV in females was 6.9/million; in males, it was 9.2/million. The annual incidence for GPA was calculated as 4.8/1,000,000, the incidence for MPA was 2.4/1,000,000, and the incidence for CSS was 0.8/1,000,000. Ten-year survival of patients with AAV was 65.3 %. The only independent poor prognostic factor in Cox's multivariate analysis was advanced age at the time of diagnosis (OR 7.5, 95 % CI 10.6-526, p = 0.043). The frequency of all AAV in northwestern Turkey was similar to that in southern Europe; however, it was lower than the frequency in Northern Europe.
Açıklama
Anahtar Kelimeler
Antineutrophil Cytoplasmic Antibody (ANCA)-Associated Vasculitis (AAV), Eosinophilic Granulomatosis With Polyangiitis (Churg-Strauss) (EGPA), Epidemiology, Granulatomatosis With Polyangiitis (Wegener) (GPA), Microscopic Polyangiitis (MPA), Primary Systemic Vasculitides, Churg-Strauss-Syndrome, Rheumatology 1990 Criteria, Giant-Cell Arteritis, Wegeners-Granulomatosis, Microscopic Polyangiitis, Polyarteritis-Nodosa, Consensus Conference, Classification, Population
Kaynak
Clinical Rheumatology
WoS Q Değeri
Q3
Scopus Q Değeri
Q2
Cilt
35
Sayı
8
