Intrauterine instillation of trichloroacetic acid is effective for the treatment of dysfunctional uterine bleeding

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dc.contributor.authorKucuk, M
dc.contributor.authorOkman, TK
dc.date.accessioned2024-06-12T11:16:41Z
dc.date.available2024-06-12T11:16:41Z
dc.date.issued2005
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: To evaluate the effectiveness of trichloroacetic acid (TCA) instillation into uterine cavity for the treatment of dysfunctional uterine bleeding (DUB). Design: Prospective clinical study. Setting: A university research hospital. Patient(s): Ninety women participated who had dysfunctional uterine bleeding. Intervention(s): Ninety-five percent of TCA was instilled in to uterine cavity for endometrial ablation in women with dysfunctional uterine bleeding who want conservative treatment. Participants in group 1 received only TCA; participants in group 2 received a single dose of gonadotropin-releasing hormone analogue 1 month before the procedure. Main Outcome Measure(s): All participants underwent an evaluation that included cycle history, body mass index measurement, and transvaginal ultrasonography of pelvis, diagnostic hysteroscopy and endometrial biopsy. Result(s): At the end of 12 months of the treatment, amenorrhea rates in group 1 and group 2 were 26.7% vs. 31.1%, with pooled amenorrhea, hypomenorrhea, and eumenorrhea rate of 95.6% vs. 97.8%, respectively. There was no significant differences between the groups vis-a-vis postprocedure results. More than 90% of women who have this procedure are satisfied with the results. There were no observed negative effects or related complications with this treatment. Conclusion(s): An instillation of TCA into uterine cavity produces acceptable results and provides conservative management of DUB. (C)2005 by American Society for Reproductive Medicine.en_US
dc.identifier.doi10.1016/j.fertnstert.2004.05.100
dc.identifier.endpage194en_US
dc.identifier.issn0015-0282
dc.identifier.issue1en_US
dc.identifier.pmid15652906en_US
dc.identifier.scopus2-s2.0-11844298450en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage189en_US
dc.identifier.urihttps://doi.org/10.1016/j.fertnstert.2004.05.100
dc.identifier.urihttps://hdl.handle.net/20.500.14551/24403
dc.identifier.volume83en_US
dc.identifier.wosWOS:000226445200026en_US
dc.identifier.wosqualityQ1en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherElsevier Science Incen_US
dc.relation.ispartofFertility And Sterilityen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTrichloroacetic Instillationen_US
dc.subjectEndometrial Ablationen_US
dc.subjectHysteroscopyen_US
dc.subjectEndometriumen_US
dc.subjectChemical Destructionen_US
dc.subjectDysfunctional Uterine Bleedingen_US
dc.subjectMetrorrhagiaen_US
dc.subjectThermal Balloon Ablationen_US
dc.subjectMicrowave Endometrial Ablationen_US
dc.subjectRandomized-Trialen_US
dc.subjectMenorrhagiaen_US
dc.subjectLaseren_US
dc.subjectAnesthesiaen_US
dc.subjectResectionen_US
dc.subjectTherapyen_US
dc.subjectSafetyen_US
dc.subjectSystemen_US
dc.titleIntrauterine instillation of trichloroacetic acid is effective for the treatment of dysfunctional uterine bleedingen_US
dc.typeArticleen_US

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