Intrauterine instillation of trichloroacetic acid is effective for the treatment of dysfunctional uterine bleeding

Küçük Resim Yok

Tarih

2005

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Elsevier Science Inc

Erişim Hakkı

info:eu-repo/semantics/openAccess

Özet

Objective: To evaluate the effectiveness of trichloroacetic acid (TCA) instillation into uterine cavity for the treatment of dysfunctional uterine bleeding (DUB). Design: Prospective clinical study. Setting: A university research hospital. Patient(s): Ninety women participated who had dysfunctional uterine bleeding. Intervention(s): Ninety-five percent of TCA was instilled in to uterine cavity for endometrial ablation in women with dysfunctional uterine bleeding who want conservative treatment. Participants in group 1 received only TCA; participants in group 2 received a single dose of gonadotropin-releasing hormone analogue 1 month before the procedure. Main Outcome Measure(s): All participants underwent an evaluation that included cycle history, body mass index measurement, and transvaginal ultrasonography of pelvis, diagnostic hysteroscopy and endometrial biopsy. Result(s): At the end of 12 months of the treatment, amenorrhea rates in group 1 and group 2 were 26.7% vs. 31.1%, with pooled amenorrhea, hypomenorrhea, and eumenorrhea rate of 95.6% vs. 97.8%, respectively. There was no significant differences between the groups vis-a-vis postprocedure results. More than 90% of women who have this procedure are satisfied with the results. There were no observed negative effects or related complications with this treatment. Conclusion(s): An instillation of TCA into uterine cavity produces acceptable results and provides conservative management of DUB. (C)2005 by American Society for Reproductive Medicine.

Açıklama

Anahtar Kelimeler

Trichloroacetic Instillation, Endometrial Ablation, Hysteroscopy, Endometrium, Chemical Destruction, Dysfunctional Uterine Bleeding, Metrorrhagia, Thermal Balloon Ablation, Microwave Endometrial Ablation, Randomized-Trial, Menorrhagia, Laser, Anesthesia, Resection, Therapy, Safety, System

Kaynak

Fertility And Sterility

WoS Q Değeri

Q1

Scopus Q Değeri

Q1

Cilt

83

Sayı

1

Künye