Cancer Treatment: An Epigenetic View

dc.authoridKalkan, Rasime/0000-0002-6095-7352
dc.authoridaydin, cansu/0000-0002-6140-6405
dc.authorwosidKalkan, Rasime/X-4808-2019
dc.contributor.authorAydin, Cansu
dc.contributor.authorKalkan, Rasime
dc.date.accessioned2024-06-12T10:55:35Z
dc.date.available2024-06-12T10:55:35Z
dc.date.issued2020
dc.departmentTrakya Üniversitesien_US
dc.description.abstractCancer can be identified as an uncontrolled growth and reproduction of cell. Accumulation of genetic aberrations (mutations of oncogenes and tumor-suppressor genes and epigenetic modifications) is one of the characteristics of cancer cell. Increasing number of studies highlighted importance of the epigenetic alterations in cancer treatment and prognosis. Now, cancer epigenetics have a huge importance for developing novel biomarkers and therapeutic target for cancer. In this review, we will provide a summary of the major epigenetic changes involved in cancer and preclinical results of epigenetic therapeutics.en_US
dc.identifier.doi10.1055/s-0040-1713610
dc.identifier.endpage7en_US
dc.identifier.issn2699-9404
dc.identifier.issue1en_US
dc.identifier.pmid32879917en_US
dc.identifier.startpage3en_US
dc.identifier.urihttps://doi.org/10.1055/s-0040-1713610
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19479
dc.identifier.volume7en_US
dc.identifier.wosWOS:000582486700002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherThieme Medical Publ Incen_US
dc.relation.ispartofGlobal Medical Geneticsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectCanceren_US
dc.subjectTreatmenten_US
dc.subjectEpigeneticsen_US
dc.subjectEpidrugsen_US
dc.subjectMethylationen_US
dc.subjectHistone Deacetylase Inhibitionen_US
dc.subjectDna Methylationen_US
dc.subjectPhase-Ien_US
dc.subjectPotential Biomarkersen_US
dc.subjectEstrogen-Receptoren_US
dc.subjectMethyltransferaseen_US
dc.subjectReexpressionen_US
dc.subjectEpigenomicsen_US
dc.subjectGenesen_US
dc.subjectDemethylationen_US
dc.titleCancer Treatment: An Epigenetic Viewen_US
dc.typeReview Articleen_US

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