Cancer Treatment: An Epigenetic View
Küçük Resim Yok
Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Thieme Medical Publ Inc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Cancer can be identified as an uncontrolled growth and reproduction of cell. Accumulation of genetic aberrations (mutations of oncogenes and tumor-suppressor genes and epigenetic modifications) is one of the characteristics of cancer cell. Increasing number of studies highlighted importance of the epigenetic alterations in cancer treatment and prognosis. Now, cancer epigenetics have a huge importance for developing novel biomarkers and therapeutic target for cancer. In this review, we will provide a summary of the major epigenetic changes involved in cancer and preclinical results of epigenetic therapeutics.
Açıklama
Anahtar Kelimeler
Cancer, Treatment, Epigenetics, Epidrugs, Methylation, Histone Deacetylase Inhibition, Dna Methylation, Phase-I, Potential Biomarkers, Estrogen-Receptor, Methyltransferase, Reexpression, Epigenomics, Genes, Demethylation
Kaynak
Global Medical Genetics
WoS Q Değeri
N/A
Scopus Q Değeri
Cilt
7
Sayı
1
