Synthesis, Spectral Analysis and Antimicrobial Activity of New Pd(II) Complexes Involving 5,6-Dimethylbenzimidazole
Küçük Resim Yok
Tarih
2023
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Higher Education Press
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
In this study, firstly, 3-bromopropanenitrile(2a), ethyl bromoacetate(2b), and 2-bromoethan-1-amine(2c) were added to 5,6-dimethylbenzimidazole(1) and symmetrically-connected N-heterocyclic carbenes(NHC)[(3a-3c)] were synthesized. Then, the NHC precursor compounds were reacted with PdCl2 and Pd(II)-NHC complexes[(4a-4c)] were obtained. The synthesized NHC precursors(3a-3c) and Pd(II)-NHC complexes(4a-4c) were characterized by different spectroscopic methods. The antibacterial activities of these products were measured against bacteria and fungus with the disc diffusion method. Pd(II)-NHC complexes had higher antibacterial activity than the NHC precursors. The synthesized compounds showed antimicrobial activity with different properties from each other. In vitro biological activities of salts and metal complexes on selected bacteria were determined by the broth dilution method based on Clinical and Laboratory Standards Institute guidelines. 1,3-Bis-(2-hydroxyethyl) imidazolinium bromide and 3-(2-ethoxy-2-oxoethyl)-1-(3-aminopropyl)-1H-imidazole-3-ium bromide had activity against Escherichia coli.
Açıklama
Anahtar Kelimeler
N-Heterocyclic Carbene, Palladium(II)-NHC Complex, Structural Analysis, Antimicrobial Activity, N-Heterocyclic Carbene, Crystal-Structure, Pt(Ii) Complexes, Palladium, Nanoparticles, Anticancer, Ligands, Heck, Nhc
Kaynak
Chemical Research In Chinese Universities
WoS Q Değeri
N/A
Scopus Q Değeri
Q2
Cilt
39
Sayı
6
