Value of biomarker-based diagnostic test in differential diagnosis of hemorrhagic-ischemic stroke

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dc.authoridkavalcı, cemil/0000-0003-2529-2946
dc.authorwosidkavalcı, cemil/AGG-1308-2022
dc.contributor.authorKavalci, C.
dc.contributor.authorGenchallac, H.
dc.contributor.authorDurukan, P.
dc.contributor.authorCevik, Y.
dc.date.accessioned2024-06-12T11:00:17Z
dc.date.available2024-06-12T11:00:17Z
dc.date.issued2011
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground and aim: Stroke is an emergency which threatens life and the third leading cause of death in developed countries and the leading cause of long-term disability. By means of this study, it was aimed to evaluate the position of triage stroke panel in differential diagnosis of acute hemorrhagic stroke and ischemic stroke and sub-types of ischemic stroke. Material and methods: Patients with acute stroke admitted to Emergency Department were prospectively recruited between June 2008-January 2009. BNP, D-dimer, MMP-9, S-100b levels were asseyed. Statistical significance for intergroup differences was assessed by Pearson's X-2 for categorical variables and Mann-Whitney U test or Kruskal-Wallis test for continuous variables. Results and conlusion: A total of 100 consecutive patients with a diagnosis of stroke were evaluated. Of these, 29 (29 %) patients had brain hemorrhages on the computed tomography scan performed the Emergency Department, 71 (71 %) patients had ischemic stroke. It was observed that the intercept obtained as a result of jointly evaluating BNP, D-dimer, MMP9 and S100b is more important in differential diagnosis (p<0.005). We suggest that using a combination of plasma biomarkers may be usefull to ischemic or hemorrhagic stroke for differential diagnosis (Tab. 4, Ref. 22). Full Text in free PDF www.bmj.sk.en_US
dc.identifier.endpage401en_US
dc.identifier.issn0006-9248
dc.identifier.issn1336-0345
dc.identifier.issue7en_US
dc.identifier.pmid21744736en_US
dc.identifier.scopus2-s2.0-79960548208en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage398en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20778
dc.identifier.volume112en_US
dc.identifier.wosWOS:000291418500007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherComenius Univen_US
dc.relation.ispartofBratislava Medical Journal-Bratislavske Lekarske Listyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectEmergencyen_US
dc.subjectStrokeen_US
dc.subjectBiomarkersen_US
dc.subjectMatrix-Metalloproteinase Expressionen_US
dc.subjectThrombolytic Therapyen_US
dc.subjectMatrix-Metalloproteinase-9en_US
dc.subjectTransformationen_US
dc.titleValue of biomarker-based diagnostic test in differential diagnosis of hemorrhagic-ischemic strokeen_US
dc.typeArticleen_US

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