Serum Oestradiol Pattern during Coasting is Different in Antagonist Cycles Compared with Long Agonist Cycles in In Vitro Fertilisation

dc.contributor.authorElter, Koray
dc.contributor.authorÖzay, Tijen Alev
dc.contributor.authorErgin, Elif
dc.contributor.authorÖzörnek, Murat Hakan
dc.date.accessioned2021-11-20T10:10:00Z
dc.date.available2021-11-20T10:10:00Z
dc.date.issued2013
dc.departmentFakülteler, Tıp Fakültesi, Cerrahi Tıp Bilimleri Bölümü, Kadın Hastalıkları ve Doğum Anabilim Dalıen_US
dc.description.abstractBackground: GnRH agonists and antagonists have different mechanism of action, and therefore serum estradiol levels might differ during coasting in IVF. Aims: To compare the change in serum oestradiol levels after withholding the gonadotropins for coasting between long agonist and antagonist cycles. Study Design: Retrospective study. Methods: Antagonist and long agonist cycles, in which coasting was performed, were analysed in this retrospective analysis. Antagonist cycles (n=50) were compared with long agonist cycles (n=52) with respect to daily serum oestradiol levels following withholding of gonadotropins. Results: The pattern of change in serum oestradiol was different between groups; it increased on the first day by 11.2% and decreased thereafter on the second and third days in the agonist group. However, it began to decrease from the first day in the antagonist group. Therefore, peak serum oestradiol levels were significantly higher in the agonist group than in the antagonist group (mean±standard deviation; 5798±1748 vs 5104±1351 pg/mL). The duration of coasting was shorter in the antagonist group compared with that in the agonist group (mean±standard deviation; 2.60±1.40 vs 1.96±0.88 days). Conclusion: Serum oestradiol pattern during coasting is different in antagonist cycles compared with long agonist cycles in in vitro fertilisation.en_US
dc.identifier.doi10.5152/balkanmedj.2013.9028en_US
dc.identifier.endpage409en_US
dc.identifier.issn2146-3123
dc.identifier.issn2146-3131
dc.identifier.issue4en_US
dc.identifier.pmid25207149en_US
dc.identifier.scopus2-s2.0-84891615037en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage406en_US
dc.identifier.trdizinid242857en_US
dc.identifier.urihttps://app.trdizin.gov.tr/makale/TWpReU9EVTNOdz09
dc.identifier.urihttps://hdl.handle.net/20.500.14551/5456
dc.identifier.volume30en_US
dc.identifier.wosWOS:000329206300011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.relation.ispartofBalkan Medical Journalen_US
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.snmz20240608_ID_Qen_US
dc.subjectCerrahien_US
dc.titleSerum Oestradiol Pattern during Coasting is Different in Antagonist Cycles Compared with Long Agonist Cycles in In Vitro Fertilisationen_US
dc.typeArticleen_US

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