Oxidative Stress in Patients with Scalp Seborrheic Dermatitis

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dc.authoridKurutas, Ergul Belge/0000-0002-6653-4801
dc.authorwosidKurutas, Ergul Belge/CAJ-2682-2022
dc.contributor.authorOzturk, Perihan
dc.contributor.authorArican, Ozer
dc.contributor.authorKurutas, Ergul Beige
dc.contributor.authorKarakas, Tugba
dc.contributor.authorKabakci, Betul
dc.date.accessioned2024-06-12T11:13:57Z
dc.date.available2024-06-12T11:13:57Z
dc.date.issued2013
dc.departmentTrakya Üniversitesien_US
dc.description.abstractSeborrheic dermatitis (SD) is a common, chronic inflammatory skin disease that mainly affects the scalp. The objective of this study was to evaluate the activities of superoxide dismutase (SOD) and catalase (CAT) and the levels of malondialdehyde (MDA) in scraping samples of patients with scalp SD. Thirty consecutive patients with a diagnosis of scalp SD and thirty-one healthy volunteers were enrolled. The samples were obtained by scraping the skin surface of the scalp. SOD and CAT activities and MDA levels were measured in scraping samples by spectrophotometric method. SOD and CAT activities and MDA levels were significantly higher in patients than in controls (p<0.001 all). There was a positive correlation between the severity of the disease and itching scores (contingency coefficient = 0.671, p<0.001). Except for this correlation, there was no significant correlation among age, sex, duration and severity of the disease, itching scores, antioxidant enzymes and MDA levels in the patient group (p>0.05). Cutaneous oxidative stress in patients with SD may play an important role in the pathogenesis of the disease. Further clinical and laboratory evaluation of the oxidant/anti-oxidant system in patients with SD is warranted.en_US
dc.identifier.endpage85en_US
dc.identifier.issn1330-027X
dc.identifier.issue2en_US
dc.identifier.pmid24001414en_US
dc.identifier.scopus2-s2.0-84882956526en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage80en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23751
dc.identifier.volume21en_US
dc.identifier.wosWOS:000323022100002en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCroation Dermatovenerological Socen_US
dc.relation.ispartofActa Dermatovenerologica Croaticaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectSeborrheic Dermatitisen_US
dc.subjectOxidative Stressen_US
dc.subjectSuperoxide Dismutaseen_US
dc.subjectCatalaseen_US
dc.subjectMalondialdehydeen_US
dc.subjectSevere Dandruffen_US
dc.subjectSeleniumen_US
dc.subjectManagementen_US
dc.subjectModerateen_US
dc.subjectShampooen_US
dc.subjectDiseaseen_US
dc.titleOxidative Stress in Patients with Scalp Seborrheic Dermatitisen_US
dc.typeArticleen_US

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