High prevalence of high-risk cutaneous squamous cell carcinoma in the thrace region of Turkey

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dc.authoridSarikaya Solak, Sezgi/0000-0002-8572-8249
dc.authoridCezik, Mert/0000-0003-1208-1656
dc.authoridGURSEL URUN, Yildiz/0000-0002-6137-8395
dc.authorwosidSarikaya Solak, Sezgi/A-4789-2016
dc.authorwosidURUN, Yıldız GURSEL/AAG-2851-2021
dc.contributor.authorSolak, Sezgi Sarikaya
dc.contributor.authorYondem, Haydar
dc.contributor.authorUrun, Yildiz Gursel
dc.contributor.authorCezik, Mert
dc.contributor.authorCan, Nuray
dc.date.accessioned2024-06-12T11:03:20Z
dc.date.available2024-06-12T11:03:20Z
dc.date.issued2020
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground: The characteristics of cutaneous squamous cell carcinoma (cSCC) may show differences according to the geographic distribution and ethnicity. Although most cSCCs are treated with surgical excision or other local interventions, high-risk cSCCs may have poor outcome. In the present study, we aimed to evaluate the clinicopathological characteristics and determine the high-risk features of cSCCs in the Thrace region of Turkey where the information on cSCCs is scarce. Methods: We retrospectively investigated the biopsy-proven cSCCs diagnosed between the years 2014 and 2018, in a tertiary university hospital and evaluated the high-risk features. Results: A total of 211 cSCCs were included. Men with cSCC were significantly younger than women with cSCC (P <.001). Almost one-half of the tumors (n = 103) were located on the lower lip. Patients with a cSCC on the lower lip were younger than those with a cSCC on the other sites. All patients with a cSCC on the ears were men. Twenty-eight percent of patients had tumor size more than 20 mm and 28% had tumor thickness more than 6 mm. Immunosuppression was present in 7.6% of patients. A total of 177 (83.9%) patients had high-risk cSCC. The local recurrence rate was 6.2%, and the metastasis rate was 5.2%. Conclusions: The Thrace region has significant number of cSCC, and high-risk features are very frequent. Clinicians should carefully evaluate the cSCCs in terms of high-risk features.en_US
dc.identifier.doi10.4103/tjd.tjd_103_20
dc.identifier.endpage89en_US
dc.identifier.issn1307-7635
dc.identifier.issn1308-5255
dc.identifier.issue4en_US
dc.identifier.scopus2-s2.0-85099469863en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage83en_US
dc.identifier.trdizinid483447en_US
dc.identifier.urihttps://doi.org/10.4103/tjd.tjd_103_20
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/483447
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21597
dc.identifier.volume14en_US
dc.identifier.wosWOS:000606859000001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherWolters Kluwer Medknow Publicationsen_US
dc.relation.ispartofTurk Dermatoloji Dergisi-Turkish Journal Of Dermatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHigh-Risken_US
dc.subjectHistopathologyen_US
dc.subjectNonmelanoma Skin Canceren_US
dc.subjectPrevalenceen_US
dc.subjectSquamous Cell Carcinomaen_US
dc.subjectNonmelanoma Skin Cancersen_US
dc.subjectPrognostic-Factorsen_US
dc.subjectRecurrenceen_US
dc.subjectEpidemiologyen_US
dc.subjectPopulationen_US
dc.subjectMetastasisen_US
dc.subjectExposureen_US
dc.titleHigh prevalence of high-risk cutaneous squamous cell carcinoma in the thrace region of Turkeyen_US
dc.typeArticleen_US

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