The frequency of vitamin B12, iron, and folic acid deficiency in the neonatal period and infancy, and the relationship with maternal levels

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dc.authoridHazar, Esra/0000-0003-0338-1040
dc.authoridHazar, Esra/0000-0003-0338-1040
dc.authorwosidHazar, Esra/ADV-6389-2022
dc.authorwosidHazar, Esra/HTN-2691-2023
dc.authorwosidHazar, Esra/AAF-6902-2022
dc.contributor.authorSayar, Esra Hazar
dc.contributor.authorOrhanee, Betul Biner
dc.contributor.authorSayar, Ersin
dc.contributor.authorNesrinTuran, Fatma
dc.contributor.authorKucuk, Mustafa
dc.date.accessioned2024-06-12T10:51:39Z
dc.date.available2024-06-12T10:51:39Z
dc.date.issued2020
dc.departmentTrakya Üniversitesien_US
dc.description.abstractAim: The most important function of vitamin B12 is to accomplish DNA synthesis, which is necessary for cell division and proliferation. Deficiency of vitamin B12 causes megaloblastic anemia, retardation of growth, and delay in neuromotor maturation. Newborns whose mothers have vitamin B12 deficiency are born with low vitamin B12 storages, and are at risk in terms of vitamin B12 deficiency symptoms during infancy. The aim of our study was to investigate the frequency of anemia and deficiency of vitamin B12, folic acid, and iron in pregnant women living in our region, in their newborn babies, and during the infancy period of these babies. Another aim of our study was to investigate the correlation between the levels of these vitamins in newborns and in their mothers. Material and Methods: In our study, 250 pregnant women at 38-42 gestational weeks, who were admitted for delivery to Gynecology and Obstetrics Clinic and their babies with a birth weight over 2500 g were included in the study. Results: We determined that 24.8% of the pregnant women had anemia, 28% had low ferritin levels, 90.4% had vitamin B 12 deficiency, and 22.4% had folic acid deficiency. Some 3.2% of the newborns had anemia, 2.8% had low ferritin levels, and 72.4% had vitamin B12 deficiency. Among the infants who presented for a follow-up visit at 6 months of age, 22.3% had anemia, 14.9% had low ferritin levels, 40.4% had vitamin B12 deficiency, and 1.06% had folic acid deficiency. In addition, we found that the levels of vitamin B12 and folic acid in newborns were related to the levels of vitamin B12 and folic acid in their mothers. Conclusion: Development of low vitamin B12 stores in newborns and the development of vitamin B12 deficiency during infancy, which may result in irreversible complications including neurologic complications, can be prevented by preventing vitamin B12 deficiency during pregnancy.en_US
dc.description.sponsorshipTrakya University Scientific Research Projects (TUBAP) Uniten_US
dc.description.sponsorshipThe study was supported by Trakya University Scientific Research Projects (TUBAP) Unit.en_US
dc.identifier.doi10.14744/TurkPediatriArs.2020.14042
dc.identifier.endpage148en_US
dc.identifier.issn1306-0015
dc.identifier.issn1308-6278
dc.identifier.issue2en_US
dc.identifier.pmid32684759en_US
dc.identifier.scopus2-s2.0-85087131685en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage139en_US
dc.identifier.trdizinid353547en_US
dc.identifier.urihttps://doi.org/10.14744/TurkPediatriArs.2020.14042
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/353547
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18442
dc.identifier.volume55en_US
dc.identifier.wosWOS:000547379400008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Pediatrics Assocen_US
dc.relation.ispartofTurk Pediatri Arsivi-Turkish Archives Of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAnemiaen_US
dc.subjectInfanten_US
dc.subjectNewbornen_US
dc.subjectPregnancyen_US
dc.subjectVitamin B12 Deficiencyen_US
dc.subjectMegaloblastic-Anemiaen_US
dc.subjectCobalamin Statusen_US
dc.subjectIndian Infantsen_US
dc.subjectFolateen_US
dc.titleThe frequency of vitamin B12, iron, and folic acid deficiency in the neonatal period and infancy, and the relationship with maternal levelsen_US
dc.typeArticleen_US

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