Serum osteopontin levels in patients with psoriasis vulgaris and its relation with oxidative stress

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dc.authorwosidKorkmaz, Selma/JRX-3713-2023
dc.contributor.authorKilinc, Cem
dc.contributor.authorKorkmaz, Selma
dc.contributor.authorOzgun, Gulben Sayilan
dc.contributor.authorFicicioglu, Sezin Kuru
dc.contributor.authorPiskin, Suleyman
dc.date.accessioned2024-06-12T11:13:05Z
dc.date.available2024-06-12T11:13:05Z
dc.date.issued2023
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground and Design: Oxidative stress is known to play a role in the etiopathogenesis of psoriasis. Recent data suggest that osteopontin (OPN) can also play a role in the pathogenesis of psoriasis. In the current study, OPN levels and oxidative stress were evaluated in patients with psoriasis.Materials and Methods: The study included 61 patients with psoriasis and 62 healthy controls. The OPN levels, total antioxidant status (TAS), total oxidant status (TOS), and oxidative stress index (OSI) were measured using serum. The disease severity was evaluated using the psoriasis area and severity index (PASI).Results: No statistically significant differences in OPN, TAS, and OSI values were identified between the psoriasis and control groups. A negative correlation was found with the TAS. There was no statistically significant correlation between the PASI score and OPN, TAS, TOS, and OSI values.Conclusion: We did not find a statistically significant correlation between OPN levels and oxidative stress in patients with psoriasis. We believe that larger and more detailed studies are needed to highlight the role of OPN and oxidative stress in the etiopathogenesis of psoriasis.en_US
dc.description.sponsorshipTrakya University Scientific Research Projects Coordination Unit [2016/41]; Trakya Universityen_US
dc.description.sponsorshipThe study was supported by Trakya University Scientific Research Projects Coordination Unit (project number: 2016/41)& nbsp;en_US
dc.identifier.doi10.4274/turkderm.galenos.2023.92845
dc.identifier.endpage65en_US
dc.identifier.issn2717-6398
dc.identifier.issn2651-5164
dc.identifier.issue2en_US
dc.identifier.scopus2-s2.0-85164385436en_US
dc.identifier.scopusqualityQ4en_US
dc.identifier.startpage61en_US
dc.identifier.trdizinid1188910en_US
dc.identifier.urihttps://doi.org/10.4274/turkderm.galenos.2023.92845
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1188910
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23408
dc.identifier.volume57en_US
dc.identifier.wosWOS:001023121000005en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofTurkderm-Turkish Archives Of Dermatology And Venerologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPsoriasisen_US
dc.subjectOsteopontinen_US
dc.subjectOxidative Stressen_US
dc.subjectEtiologyen_US
dc.subjectCapacityen_US
dc.subjectSkinen_US
dc.titleSerum osteopontin levels in patients with psoriasis vulgaris and its relation with oxidative stressen_US
dc.typeArticleen_US

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