Serum neutrophil-lymphocyte ratios, C-reactive protein and sedimentation levels in Parkinson's disease

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dc.authoridAksoy, Dürdane/0000-0003-1981-084X;
dc.authorwosidAksoy, Dürdane/B-7835-2017
dc.authorwosidbenli, ismail/A-7441-2016
dc.contributor.authorSolmaz, Volkan
dc.contributor.authorGenc, Elmas Pekdas
dc.contributor.authorAksoy, Durdane
dc.contributor.authorCevik, Betul
dc.contributor.authorKurt, Semiha Gulsum
dc.contributor.authorBenli, Ismail
dc.date.accessioned2024-06-12T11:03:39Z
dc.date.available2024-06-12T11:03:39Z
dc.date.issued2018
dc.departmentTrakya Üniversitesien_US
dc.description.abstractPurpose: We aimed to investigate the systemic inflammation status by analyzing the Neutrophil/Lymphocyte (N/L) ratio, Erythrocyte Sedimentation Rate (ESR), and C - reactive protein (CRP) in patients with Parkinson's disease (PD). Materials and Methods: 101 PD patients, and 60 healthy subjects of similar age and gender were include in this study. The demographic data and duration of the disease, the drugs, duration of usage of Parkinson drugs, Hoehn-Yahr stage were noted. After full neurological examination blood samples are collected and neutrophil, lymphocyte counts, high sensitive CRP, ESR levels are detected. Results: The N/L ratio and the CRP levels were statistically higher in Parkinson's group. There was a statistically significant but weak positive correlation between the CRP levels and the N/L ratio with the disease duration. Similarly, there was a statistically significant but weak positive correlation between the CRP levels and the N/L ratios with Hoehn-Yahr stages. When the N/L rates of the Parkinson's patients were correlated with the CRP and the ESR levels separately, it was observed that there was a weak but statistically significant correlation between the CRP and the N/L ratio Conclusion: N/L ratio, and CRP levels, which are very important indicators of peripheral inflammation, was higher in PD. Our findings suggest that these biochemical markers may have a predictive value for the diagnosis of PD.en_US
dc.identifier.doi10.17826/cumj.341649
dc.identifier.endpage311en_US
dc.identifier.issn2602-3032
dc.identifier.issn2602-3040
dc.identifier.issue2en_US
dc.identifier.startpage305en_US
dc.identifier.trdizinid295398en_US
dc.identifier.urihttps://doi.org/10.17826/cumj.341649
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/295398
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21743
dc.identifier.volume43en_US
dc.identifier.wosWOS:000437950000006en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherCukurova Univ, Fac Medicineen_US
dc.relation.ispartofCukurova Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIdiopathic Parkinson Diseaseen_US
dc.subjectNeutrophil-Lymphocyte Ratioen_US
dc.subjectCRPen_US
dc.subjectPeripheral Inflammationen_US
dc.subjectAlzheimers-Diseaseen_US
dc.subjectInflammationen_US
dc.subjectProgressionen_US
dc.subjectOnseten_US
dc.subjectAgeen_US
dc.titleSerum neutrophil-lymphocyte ratios, C-reactive protein and sedimentation levels in Parkinson's diseaseen_US
dc.typeArticleen_US

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