Osteoblast behaviour on zirconia fabricated by additive and subtractive technology

Basit Öğe Kaydı
dc.authoridKurt, Aysegul/0000-0003-2775-3179
dc.authoridRoser, Christoph J./0000-0002-7556-1510
dc.authoridErber, Ralf/0000-0001-9689-2151
dc.authorwosidKurt, Aysegul/HJH-9446-2023
dc.authorwosidRoser, Christoph J./KMA-2760-2024
dc.contributor.authorRoser, Christoph J.
dc.contributor.authorErber, Ralf
dc.contributor.authorRammelsberg, Peter
dc.contributor.authorLux, Christopher J.
dc.contributor.authorKurt, Aysegul
dc.contributor.authorRues, Stefan
dc.contributor.authorSchwindling, Franz Sebastian
dc.date.accessioned2024-06-12T10:50:40Z
dc.date.available2024-06-12T10:50:40Z
dc.date.issued2023
dc.departmentTrakya Üniversitesien_US
dc.description.abstractZirconia is an attractive material for the manufacturing of oral implants and patient-individual barriers for guided bone regeneration. This study compared osteoblast behaviour on additive manufactured and milled 3-mol % yttria-stabilized tetragonal polycrystal zirconia (ZrO2).Two groups of samples (O5 x 2 mm) were manufactured by stereolithography (LithaCon 230, Lithoz, Vienna, Austria) and subsequently heat-treated and sintered. One group remained superficially unmodified (AM-ZrO2unmod.), while the other was polished according to DIN EN ISO 6872 standard using automated grinding (AMZrO2-pol.). For comparison, milled samples (e.max ZirCAD LT, Ivoclar Vivadent, Schaan, Liechtenstein) were sintered and polished similarly (Mil-ZrO2-pol.). Surface roughness was characterized using tactile profilometry. Adhesion, proliferation and coverage of human fetal osteoblasts (hFOB 1.19) as well as expression of osteogenic marker genes ALPL and RUNX2 were determined (and statistically compared using Kruskal-Wallis-analyses and Dunn's Post-hoc-tests).The surface roughness of AM-ZrO2-unmod. Was 45 times higher than that of the polished groups. No significant differences were detected between the three groups regarding cell adhesion and proliferation. With regard to cell coverage, AM-ZrO2-pol. Significantly outperformed the two other groups (p < 0.05). ALPL- and RUNX2mRNA expression was insignificantly superior for AM-ZrO2-unmod. Compared to the two other groups. Therefor no detrimental effect on osteoblast behaviour caused by the investigated, acrylic binder-based 3D printing workflow was observed.en_US
dc.description.sponsorshipDietmar Hopp Foundation [1DH1911472]en_US
dc.description.sponsorshipFunding This study was supported by the Dietmar Hopp Foundation, Ger- many, grant number 1DH1911472.en_US
dc.identifier.doi10.1016/j.ceramint.2022.11.030
dc.identifier.endpage8800en_US
dc.identifier.issn0272-8842
dc.identifier.issn1873-3956
dc.identifier.issue6en_US
dc.identifier.scopus2-s2.0-85141507131en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage8793en_US
dc.identifier.urihttps://doi.org/10.1016/j.ceramint.2022.11.030
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18085
dc.identifier.volume49en_US
dc.identifier.wosWOS:000944224600001en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherElsevier Sci Ltden_US
dc.relation.ispartofCeramics Internationalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAdditive Manufacturingen_US
dc.subjectZirconiaen_US
dc.subjectImplanten_US
dc.subject3D Printingen_US
dc.subjectCADen_US
dc.subjectCAMen_US
dc.subjectSurface-Topographyen_US
dc.subjectMolar Replacementen_US
dc.subjectDental Implantsen_US
dc.subjectIn-Vitroen_US
dc.subjectTitaniumen_US
dc.subjectImmediateen_US
dc.subjectCad/Camen_US
dc.subjectCeramicsen_US
dc.titleOsteoblast behaviour on zirconia fabricated by additive and subtractive technologyen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu