Risk of premature coronary atherosclerosis in patients with nonalcoholic fatty liver disease

dc.authoridTAYLAN, GOKAY/0000-0002-7015-4537
dc.authoridKaya, Caglar/0000-0002-2968-5352
dc.authorid, Grigorie/0000-0003-4514-4537
dc.authoridEBIK, MUSTAFA/0000-0002-0585-0958
dc.authorwosidTAYLAN, GOKAY/HJZ-4693-2023
dc.authorwosidKaya, Caglar/GSN-9700-2022
dc.contributor.authorTaylan, Gokay
dc.contributor.authorEbik, Mustafa
dc.contributor.authorSolak, Serdar
dc.contributor.authorKaya, Caglar
dc.contributor.authorYalta, Kenan
dc.date.accessioned2024-06-12T10:52:46Z
dc.date.available2024-06-12T10:52:46Z
dc.date.issued2022
dc.departmentTrakya Üniversitesien_US
dc.description.abstractOBJECTIVE: In the current literature, there are few studies investigating the relationship between premature coronary atherosclerosis and nonalcoholic fatty liver disease. We aimed to evaluate the relationship between nonalcoholic fatty liver disease and premature coronary atherosclerosis. METHODS: In this cross-sectional study, female patients aged <55 years and male patients aged <50 years were enrolled. Both male and female patients underwent coronary angiography and abdomen ultrasonography between 2014 and 2019. A stepwise binary logistic regression analysis was carried out to evaluate the independent variables related to premature coronary atherosclerosis and nonalcoholic fatty liver disease. A p-value<0.05 was considered statistically significant. RESULTS: nonalcoholic fatty liver disease was present in 44% of patients (n=377). Notably, 62% of the patients were female and the mean age was 44.5 (39-49) years. In a multivariate analysis, nonalcoholic fatty liver disease was shown to be an independent risk factor of premature coronary atherosclerosis (OR 1.438; 95%CI, 1.050-1.969; p=0.024). CONCLUSIONS: The presence of nonalcoholic fatty liver disease is an important independent risk factor for the development of premature coronary atherosclerosis.en_US
dc.identifier.doi10.1590/1806-9282.20220514
dc.identifier.endpage1433en_US
dc.identifier.issn0104-4230
dc.identifier.issn1806-9282
dc.identifier.issue10en_US
dc.identifier.pmid36417648en_US
dc.identifier.scopus2-s2.0-85142939221en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1428en_US
dc.identifier.urihttps://doi.org/10.1590/1806-9282.20220514
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18824
dc.identifier.volume68en_US
dc.identifier.wosWOS:000913824800019en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherAssoc Medica Brasileiraen_US
dc.relation.ispartofRevista Da Associacao Medica Brasileiraen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAtherosclerosisen_US
dc.subjectCoronary Artery Diseaseen_US
dc.subjectNonalcoholic Fatty Liver Diseaseen_US
dc.subjectArtery-Diseaseen_US
dc.subjectAssociationen_US
dc.subjectSeverityen_US
dc.subjectSteatosisen_US
dc.subjectPlaquesen_US
dc.titleRisk of premature coronary atherosclerosis in patients with nonalcoholic fatty liver diseaseen_US
dc.typeArticleen_US

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