Risk factors for persistence of coronary artery abnormalities in Turkish children with Kawasaki disease

dc.authoridVupa Çilengiroğlu, Özgül/0000-0003-0181-8376
dc.authoridMese, Timur/0000-0002-4433-3929
dc.authoridGokalp, Selman/0000-0003-3812-2081
dc.authorwosidVupa Çilengiroğlu, Özgül/JFK-9235-2023
dc.authorwosidYılmazer, Murat Muhtar/AAY-7032-2021
dc.authorwosidMese, Timur/AAJ-1231-2020
dc.authorwosidMese, Timur/T-4074-2019
dc.authorwosidGokalp, Selman/C-7730-2019
dc.contributor.authorYilmazer, Murat Muhtar
dc.contributor.authorOner, Taliha
dc.contributor.authorGokalp, Selman
dc.contributor.authorDoksoz, Onder
dc.contributor.authorGuven, Baris
dc.contributor.authorVupa-Cilengiroglu, Ozgur
dc.contributor.authorMese, Timur
dc.date.accessioned2024-06-12T10:58:37Z
dc.date.available2024-06-12T10:58:37Z
dc.date.issued2015
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe aim of this study was to identify the risk factors for persistence of coronary artery abnormalities (CAAs) in Kawasaki disease and to compare the differences between complete (n=25) and incomplete (n=18) forms of the disease in relation to CAAs. The patients' demographic (age and sex), clinical (season of admission, duration of fever, form of Kawasaki disease), laboratory (complete blood count, eosinophil count, serum biochemistry, C-reactive protein level, erythrocyte sedimentation rate [ESR], urinary analysis), echocardiographic and therapeutic data were evaluated retrospectively from the medical records. The incidence of sterile pyuria was nearly twofold greater in patients with initial CAAs than in patients in which CAAs were not present (25% and 13%, respectively; p=0.33). In multivariate logistic regression analysis, ESR and pyuria were found to be associated with persistence of CAAs (p=0.035 and p=0.046, respectively). In addition, we found that duration of fever was significantly associated with persistence of CAAs (p=0.045). However, gender, age at presentation, peripheral blood eosinophilia, low albumin level, CRP, leukocytosis and anemia were not predictive for persistence of CAAs. There was no difference between the complete and incomplete form of the disease in regard to persistence of CAAs. As a result, we have determined that duration of fever, high levels of ESR and presence of sterile pyuria can be used to predict the persistence of CAAs in Kawasaki disease.en_US
dc.identifier.endpage253en_US
dc.identifier.issn0041-4301
dc.identifier.issue3en_US
dc.identifier.pmid26701943en_US
dc.identifier.scopus2-s2.0-84951784935en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage248en_US
dc.identifier.trdizinid239695en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/239695
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20131
dc.identifier.volume57en_US
dc.identifier.wosWOS:000367571800007en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish J Pediatricsen_US
dc.relation.ispartofTurkish Journal Of Pediatricsen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectCoronary Involvementen_US
dc.subjectKawasaki Diseaseen_US
dc.subjectPersistencyen_US
dc.subjectPyuriaen_US
dc.subjectFeveren_US
dc.subjectAmerican-Heart-Associationen_US
dc.subjectLymph-Node Syndromeen_US
dc.subjectGamma-Globulinen_US
dc.subjectSterile Pyuriaen_US
dc.subjectDiagnosisen_US
dc.titleRisk factors for persistence of coronary artery abnormalities in Turkish children with Kawasaki diseaseen_US
dc.typeArticleen_US

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