Evaluation of residual monomer release and toxicity of self-adhesive resin cements

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dc.authoridKocyigit, Abdurrahim/0000-0003-2335-412X
dc.authoridKurt, Aysegul/0000-0003-2775-3179
dc.authoridKurt, Aysegul/0000-0003-2775-3179
dc.authoridGuler, Eray Metin/0000-0003-4351-1719
dc.authorwosidKocyigit, Abdurrahim/P-8685-2019
dc.authorwosidKurt, Aysegul/Y-9162-2019
dc.authorwosidAltintas, Subutay Han/AAS-5324-2020
dc.authorwosidKurt, Aysegul/HJH-9446-2023
dc.authorwosidUsumez, Aslihan/Z-4568-2019
dc.authorwosidGuler, Eray Metin/T-6699-2017
dc.contributor.authorKurt, Aysegul
dc.contributor.authorAltintas, Subutay Han
dc.contributor.authorKiziltas, Mustafa Volkan
dc.contributor.authorTekkeli, Serife Evrim
dc.contributor.authorGuler, Eray Metin
dc.contributor.authorKocyigit, Abdurrahim
dc.contributor.authorUsumez, Aslihan
dc.date.accessioned2024-06-12T11:13:59Z
dc.date.available2024-06-12T11:13:59Z
dc.date.issued2018
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe aim of this study was to evaluate the amount of leached residual monomers from self-adhesive resin cements and evaluate their toxicity in-vitro. A total of 60 disk-shaped specimens (5 mm in diameter and 0.5 mm in thickness) were prepared from each cement (RelyX U200, SpeedCEM, G-Cem) (n=20). Specimens were immersed in artificial saliva and the amount of released monomers [urethane dimethacrylate (UDMA) and triethyleneglycol dimethacrylate (TEGDMA)] was identified. Then, the cytotoxicity and genotoxicity effect on cells were evaluated using the defined amounts of released monomers from cements. The highest monomer release was detected in G-Cem (p<0.05). The highest cytotoxicity value was identified from SpeedCEM (p<0.01) and the highest genotoxicity values were calculated from RelyX U200 (p<0.05). Released UDMA and TEGDMA from self-adhesive resin cements induced cytotoxicity and genotoxicity effect on cells.en_US
dc.description.sponsorshipResearch Support Unit of Bezmialem Vakif University in Istanbul, the Turkey [6.2014/26]en_US
dc.description.sponsorshipThe work was supported by the Research Support Unit of Bezmialem Vakif University in Istanbul, the Turkey (project no. 6.2014/26).en_US
dc.identifier.doi10.4012/dmj.2016-380
dc.identifier.endpage48en_US
dc.identifier.issn0287-4547
dc.identifier.issue1en_US
dc.identifier.pmid29225277en_US
dc.identifier.scopus2-s2.0-85041310841en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage40en_US
dc.identifier.urihttps://doi.org/10.4012/dmj.2016-380
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23764
dc.identifier.volume37en_US
dc.identifier.wosWOS:000430646900006en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJapanese Soc Dental Materials Devicesen_US
dc.relation.ispartofDental Materials Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectSelf-Adhesive Resin Cementen_US
dc.subjectMonomer Releaseen_US
dc.subjectCytotoxicityen_US
dc.subjectGenotoxicityen_US
dc.subjectElectrophoresis Comet Assayen_US
dc.subjectHuman Gingival Fibroblastsen_US
dc.subjectSealants In-Vitroen_US
dc.subjectDental Compositeen_US
dc.subjectDna-Damageen_US
dc.subjectPulp Cellsen_US
dc.subjectCytotoxicityen_US
dc.subjectComponentsen_US
dc.subjectLymphocytesen_US
dc.subjectGlutathioneen_US
dc.titleEvaluation of residual monomer release and toxicity of self-adhesive resin cementsen_US
dc.typeArticleen_US

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