Evaluation of residual monomer release and toxicity of self-adhesive resin cements
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Japanese Soc Dental Materials Devices
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
The aim of this study was to evaluate the amount of leached residual monomers from self-adhesive resin cements and evaluate their toxicity in-vitro. A total of 60 disk-shaped specimens (5 mm in diameter and 0.5 mm in thickness) were prepared from each cement (RelyX U200, SpeedCEM, G-Cem) (n=20). Specimens were immersed in artificial saliva and the amount of released monomers [urethane dimethacrylate (UDMA) and triethyleneglycol dimethacrylate (TEGDMA)] was identified. Then, the cytotoxicity and genotoxicity effect on cells were evaluated using the defined amounts of released monomers from cements. The highest monomer release was detected in G-Cem (p<0.05). The highest cytotoxicity value was identified from SpeedCEM (p<0.01) and the highest genotoxicity values were calculated from RelyX U200 (p<0.05). Released UDMA and TEGDMA from self-adhesive resin cements induced cytotoxicity and genotoxicity effect on cells.
Açıklama
Anahtar Kelimeler
Self-Adhesive Resin Cement, Monomer Release, Cytotoxicity, Genotoxicity, Electrophoresis Comet Assay, Human Gingival Fibroblasts, Sealants In-Vitro, Dental Composite, Dna-Damage, Pulp Cells, Cytotoxicity, Components, Lymphocytes, Glutathione
Kaynak
Dental Materials Journal
WoS Q Değeri
Q3
Scopus Q Değeri
Q1
Cilt
37
Sayı
1
