Increased Frequency of Gastrointestinal Symptoms in Patients with Fibromyalgia and Associated Factors: A Comparative Study

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dc.authoridUmit, Hasan/0000-0002-3651-4180
dc.authorwosidUmit, Hasan/T-6236-2019
dc.contributor.authorPamuk, Omer Nuri
dc.contributor.authorUmit, Hasan
dc.contributor.authorHarmandar, Orbay
dc.date.accessioned2024-06-12T11:01:53Z
dc.date.available2024-06-12T11:01:53Z
dc.date.issued2009
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective. To determine the frequency and severity of gastrointestinal (GI) symptoms in patients with fibromyalgaia (FM). Methods. We included 152 women with FM (mean age 45.4 +/- 12.2 yrs), 98 women with rheumatoid arthritis (RA; mean age 45.5 +/- 12.3 yrs), and 60 healthy female controls (mean age 44 +/- 11.3 yrs). All patients were questioned about the severity of their chronic widespread pain, symptoms of FM, symptoms of dyspepsia, using a visual analog scale (VAS), and anxiety-depression scale. Patients were asked self-reported (yes/no), symptom-based (>= 2 criteria) constipation and severity of constipation questions, and about the severity of quality of life (QOL) disturbance secondary to dyspepsia and constipation. Results. Patients with FM had higher symptom severities for belching, reflux, bloating, sour taste, and vomiting than patients with RA and controls (all p values < 0.01). Patients with FM had significantly more dyspepsia-related QOL disturbances than the other 2 groups (p < 0.01). FM and RA patients had more frequent self-reported constipation than controls (respectively, 42.1%, 48%, 21.7%; p < 0.01). The frequency of symptom-based constipation was significantly higher in the RA group (49%) than in FM (29.6%) and control groups (23.3%) (p < 0.01). Constipation-related QOL disturbance was significantly higher in patients with FM than in controls (p < 0.01). Conclusion. In patients with FM, the severity scores of dyspepsia symptoms, constipation, and dyspepsia-related QOL disturbance were higher than in patients with RA and controls. The higher GI symptom severity in patients with FM might have negative effects on their QOL. (First Release July 1 2009; 1 Rheumatol 2009;36:1720-4 doi: 10.3899/jrheum.090024)en_US
dc.identifier.doi10.3899/jrheum.090024
dc.identifier.endpage1724en_US
dc.identifier.issn0315-162X
dc.identifier.issn1499-2752
dc.identifier.issue8en_US
dc.identifier.pmid19567625en_US
dc.identifier.scopus2-s2.0-68849092813en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage1720en_US
dc.identifier.urihttps://doi.org/10.3899/jrheum.090024
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21068
dc.identifier.volume36en_US
dc.identifier.wosWOS:000269164700029en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJ Rheumatol Publ Coen_US
dc.relation.ispartofJournal Of Rheumatologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectFIBROMYALGIAen_US
dc.subjectRHEUMATOID ARTHRITISen_US
dc.subjectDYSPEPSIAen_US
dc.subjectCONSTIPATIONen_US
dc.subjectQUALITY OF LIFEen_US
dc.subjectIrritable-Bowel-Syndromeen_US
dc.subjectFunctional Dyspepsiaen_US
dc.subjectAnxietyen_US
dc.subjectSensitizationen_US
dc.subjectSomatizationen_US
dc.subjectConstipationen_US
dc.subjectDysfunctionen_US
dc.subjectDepressionen_US
dc.titleIncreased Frequency of Gastrointestinal Symptoms in Patients with Fibromyalgia and Associated Factors: A Comparative Studyen_US
dc.typeArticleen_US

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