Increased Frequency of Gastrointestinal Symptoms in Patients with Fibromyalgia and Associated Factors: A Comparative Study
Küçük Resim Yok
Tarih
2009
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
J Rheumatol Publ Co
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective. To determine the frequency and severity of gastrointestinal (GI) symptoms in patients with fibromyalgaia (FM). Methods. We included 152 women with FM (mean age 45.4 +/- 12.2 yrs), 98 women with rheumatoid arthritis (RA; mean age 45.5 +/- 12.3 yrs), and 60 healthy female controls (mean age 44 +/- 11.3 yrs). All patients were questioned about the severity of their chronic widespread pain, symptoms of FM, symptoms of dyspepsia, using a visual analog scale (VAS), and anxiety-depression scale. Patients were asked self-reported (yes/no), symptom-based (>= 2 criteria) constipation and severity of constipation questions, and about the severity of quality of life (QOL) disturbance secondary to dyspepsia and constipation. Results. Patients with FM had higher symptom severities for belching, reflux, bloating, sour taste, and vomiting than patients with RA and controls (all p values < 0.01). Patients with FM had significantly more dyspepsia-related QOL disturbances than the other 2 groups (p < 0.01). FM and RA patients had more frequent self-reported constipation than controls (respectively, 42.1%, 48%, 21.7%; p < 0.01). The frequency of symptom-based constipation was significantly higher in the RA group (49%) than in FM (29.6%) and control groups (23.3%) (p < 0.01). Constipation-related QOL disturbance was significantly higher in patients with FM than in controls (p < 0.01). Conclusion. In patients with FM, the severity scores of dyspepsia symptoms, constipation, and dyspepsia-related QOL disturbance were higher than in patients with RA and controls. The higher GI symptom severity in patients with FM might have negative effects on their QOL. (First Release July 1 2009; 1 Rheumatol 2009;36:1720-4 doi: 10.3899/jrheum.090024)
Açıklama
Anahtar Kelimeler
FIBROMYALGIA, RHEUMATOID ARTHRITIS, DYSPEPSIA, CONSTIPATION, QUALITY OF LIFE, Irritable-Bowel-Syndrome, Functional Dyspepsia, Anxiety, Sensitization, Somatization, Constipation, Dysfunction, Depression
Kaynak
Journal Of Rheumatology
WoS Q Değeri
Q2
Scopus Q Değeri
Q1
Cilt
36
Sayı
8
