Serum adropin levels in psoriasis vulgaris and its relation with metabolic parameters

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dc.authorwosidKorkmaz, Selma/JRX-3713-2023
dc.authorwosidKorkmaz, Selma/W-4142-2017
dc.contributor.authorKorkmaz, Selma
dc.contributor.authorSayilan Ozgun, Gulben
dc.date.accessioned2024-06-12T11:13:05Z
dc.date.available2024-06-12T11:13:05Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBackground/aim: Adropin is a peptide-structure hormone that plays a role in preventing the development of insulin resistance, which has been linked to obesity and metabolic regulation. The purpose of this study is to assess serum adropin levels and their relationship with metabolic parameters in psoriasis vulgaris patients both with and without metabolic syndrome (MetS). Materials and methods: Fifty-three patients and 26 healthy controls were included in this study. Serum adropin levels, fasting blood glucose, fasting serum insulin, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, total cholesterol, and triglyceride levels of all participants were analyzed. Enzyme-linked immunosorbent assay was used to measure serum adropin levels. Results: Serum adropin levels were 2.94 +/- 0.56 ng/mL in psoriatic patients without MetS, 2.49 +/- 0.77 ng/mL in psoriasis patients with MetS, and 3.37 +/- 10.71 ng/mL in the control group. Multivariate logistic regression analysis was used to evaluate adropin decreases in psoriasis patients as an independent predictor of the presence of MetS. Conclusion: The serum levels of adropin in psoriasis patients were significantly lower in the presence of MetS, and this decrease was more prominent than in those without MetS. Adropin may be a contributing factor for metabolic disorders and the development of MetS in psoriasis patients.en_US
dc.identifier.doi10.3906/sag-1712-192
dc.identifier.endpage115en_US
dc.identifier.issn1300-0144
dc.identifier.issn1303-6165
dc.identifier.issue1en_US
dc.identifier.pmid30762319en_US
dc.identifier.scopus2-s2.0-85061606629en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage110en_US
dc.identifier.trdizinid335764en_US
dc.identifier.urihttps://doi.org/10.3906/sag-1712-192
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/335764
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23406
dc.identifier.volume49en_US
dc.identifier.wosWOS:000458367000016en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTubitak Scientific & Technological Research Council Turkeyen_US
dc.relation.ispartofTurkish Journal Of Medical Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectPsoriasisen_US
dc.subjectMetabolic Syndromeen_US
dc.subjectAdropinen_US
dc.subjectEndothelial Dysfunctionen_US
dc.subjectInsulin-Resistanceen_US
dc.subjectPlasma Adropinen_US
dc.subjectDiseaseen_US
dc.subjectRisken_US
dc.subjectHypertensionen_US
dc.subjectAssociationen_US
dc.titleSerum adropin levels in psoriasis vulgaris and its relation with metabolic parametersen_US
dc.typeArticleen_US

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