New synthesis of novel 1,2-dihydrofuro[3,4-d]pyrimidines

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dc.authoridSuekinci Yilmaz, Aysen/0000-0002-1928-0204
dc.authorwosidYılmaz, Ayşen/AAZ-5757-2020
dc.contributor.authorYilmaz, Aysen Suekinci
dc.contributor.authorKacan, Mesut
dc.date.accessioned2024-06-12T11:13:11Z
dc.date.available2024-06-12T11:13:11Z
dc.date.issued2017
dc.departmentTrakya Üniversitesien_US
dc.description.abstractWe describe the synthesis of a novel class of compounds, 1,2-dihydrofuro[3,4-d]pyrimidines (15, 16, 18, 20) starting from dimethyl furan-3,4-dicarboxylate 6. Synthesis of these compounds consist of two basic parts: Formation of 4-(2-azido-2-oxoethyl)furan-3-carbonyl azide 11 by eight organic reactions and formation of final products by intramolecular cyclization after two selective Curtius rearrangements of acyl azides 11. (C) 2017 Elsevier Ltd. All rights reserved.en_US
dc.description.sponsorshipTrakya University Scientific Research Projects Coordination Unit [TUBAP 2012/103]en_US
dc.description.sponsorshipThe authors indebted to Trakya University Scientific Research Projects Coordination Unit (TUBAP 2012/103) for financial support for this work. We thank Technology Research and Development Application and Research Center (TUTAGEM) for the Q-TOF and IR analyses.en_US
dc.identifier.doi10.1016/j.tet.2017.05.072
dc.identifier.endpage4512en_US
dc.identifier.issn0040-4020
dc.identifier.issue31en_US
dc.identifier.scopus2-s2.0-85020082660en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage4509en_US
dc.identifier.urihttps://doi.org/10.1016/j.tet.2017.05.072
dc.identifier.urihttps://hdl.handle.net/20.500.14551/23457
dc.identifier.volume73en_US
dc.identifier.wosWOS:000405977600001en_US
dc.identifier.wosqualityQ2en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherPergamon-Elsevier Science Ltden_US
dc.relation.ispartofTetrahedronen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectPyrimidineen_US
dc.subjectFuro[3,4-D]Pyrimidineen_US
dc.subjectAcyl Azideen_US
dc.subjectCurtius Rearrangementen_US
dc.subjectIntramolecular Cyclizationen_US
dc.subjectNucleosidesen_US
dc.subjectAnalogsen_US
dc.titleNew synthesis of novel 1,2-dihydrofuro[3,4-d]pyrimidinesen_US
dc.typeArticleen_US

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