New synthesis of novel 1,2-dihydrofuro[3,4-d]pyrimidines
Küçük Resim Yok
Tarih
2017
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Pergamon-Elsevier Science Ltd
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
We describe the synthesis of a novel class of compounds, 1,2-dihydrofuro[3,4-d]pyrimidines (15, 16, 18, 20) starting from dimethyl furan-3,4-dicarboxylate 6. Synthesis of these compounds consist of two basic parts: Formation of 4-(2-azido-2-oxoethyl)furan-3-carbonyl azide 11 by eight organic reactions and formation of final products by intramolecular cyclization after two selective Curtius rearrangements of acyl azides 11. (C) 2017 Elsevier Ltd. All rights reserved.
Açıklama
Anahtar Kelimeler
Pyrimidine, Furo[3,4-D]Pyrimidine, Acyl Azide, Curtius Rearrangement, Intramolecular Cyclization, Nucleosides, Analogs
Kaynak
Tetrahedron
WoS Q Değeri
Q2
Scopus Q Değeri
Q2
Cilt
73
Sayı
31
