SCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIES

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dc.authoridOzek, Gulmira/0000-0001-8908-6098
dc.contributor.authorGoger, Gamze
dc.contributor.authorCevik, Esma
dc.contributor.authorVarnali, Alisan
dc.contributor.authorYaylaci, Omer Koray
dc.contributor.authorUma, Medine Munevver
dc.contributor.authorOzek, Gulmira
dc.date.accessioned2024-06-12T10:50:22Z
dc.date.available2024-06-12T10:50:22Z
dc.date.issued2023
dc.departmentTrakya Üniversitesien_US
dc.description.abstractThe main aim of this study is antimicrobial screening of the n-hexane, ethyl acetate and aqueous extracts obtained from aerial parts of Achillea setacea Waldst. & Kit. and Achillea coarctata Poir. against the bacterial strains Escherichia coli ATCC 8739, Staphylococcus aureus ATCC 14028 and the yeast Candida albicans ATCC 6633 by the microdilution method. In addition, the effect of the aqueous extract of A. coarctata combined with fluconazole againts C. albicans ATCC 6633, C. parapsilosis ATCC 22019, C. tropicalis ATCC 750 and C. glabrata ATCC 90030 was tested with the checkerboard method. The chemical components of the volatiles and fatty acid methyl esters were identified using the Gas Chromatography (GC) and Gas Chromatography/Mass Spectrometry (GC/MS) techniques. The main components of the volatile oil were found to be 1,8-cineole (16.1%) and beta-pinene (14.5%) for A. setacea and camphor (35.4%) and borneol (12.9%) for A. coarctata. The ethyl acetate extracts of A. setacea (MIC=156.25 mu g/mL) and A. coarctata (MIC=312.5 mu g/mL) were found more active against the tested Candida Berkh. species. The combination of aqueous extract of A. coarctata with fluconazole showed additive effect for the tested Candida species with FIC values within the range of 0.53-0.625 mu g/mL.en_US
dc.description.sponsorshipScientific and Technological Research Council of Turkye (TUBITAK) [SBAG 218s812]en_US
dc.description.sponsorshipThe study was partially supported by the Scientific and Technological Research Council of Turkye (TUBITAK) with project number SBAG 218s812.en_US
dc.identifier.doi10.23902/trkjnat.1322140
dc.identifier.endpage75en_US
dc.identifier.issn2528-9691
dc.identifier.issue2en_US
dc.identifier.startpage67en_US
dc.identifier.trdizinid1201959en_US
dc.identifier.urihttps://doi.org/10.23902/trkjnat.1322140
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/1201959
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17979
dc.identifier.volume24en_US
dc.identifier.wosWOS:001088177900008en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherTrakya Univ Balkan Yerlesesi Enstituler Binasien_US
dc.relation.ispartofTrakya University Journal Of Natural Sciencesen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAchillea Setaceaen_US
dc.subjectAchillea Coarctataen_US
dc.subjectPhytochemical Analysesen_US
dc.subjectGC/MSen_US
dc.subjectCheckerboarden_US
dc.subjectAdditive Effecten_US
dc.subjectEssential Oilsen_US
dc.subjectCombinationen_US
dc.subjectL.en_US
dc.titleSCREENING OF Achillea coarctata Poir. AND Achillea setacea Waldst. & Kit. (Asteraceae) FOR THEIR VOLATILE AND FATTY ACIDS COMPOSITIONS, AND ANTIMICROBIAL ACTIVITIESen_US
dc.typeArticleen_US

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Trakya University Journal of Natural Sciences