Evaluation of Index of Cardioelectrophysiological Balance (iCEB) in Patients with Rheumatoid Arthritis

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dc.authoridTAYLAN, GOKAY/0000-0002-7015-4537;
dc.authorwosidTAYLAN, GOKAY/HJZ-4693-2023
dc.authorwosidyilmaztepe, mustafa/AGE-8367-2022
dc.contributor.authorUcar, Fatih Mehmet
dc.contributor.authorYilmaztepe, Mustafa Adem
dc.contributor.authorTaylan, Gokay
dc.date.accessioned2024-06-12T11:03:45Z
dc.date.available2024-06-12T11:03:45Z
dc.date.issued2018
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: Index of cardioelectrophysiological balance (iCEB), measured as QT interval divided by QRS duration, is defined recently as a new risk marker for arrhythmias. Increased or decreased iCEB is associated with malignant ventricular arrhythmias. We aimed to investigate the ventricular balance between the depolarization (changes in QRS duration) and depolarization (changes in the QT interval) of the cardiac action potential in rheumatoid arthritis (RA) patients by using iCEB. Materials and Methods: In total, 60 patients (mean age was 49.4 +/- 11.7 y and 61% of the patients were female) with RA and 60 control subjects (45.3 +/- 12.6 y and 60% of the patients were female) were enrolled. iCEB (QT/QRS) and iCEBc (heart rate-corrected QT (QTc)/QRS) rates were calculated from the 12-lead electrocardiogram. Results: iCEB and iCEBc were significantly higher in patients with RA than in control subjects (p<0.001 and p<0.001, respectively), and they were correlated with high-sensitivity C-reactive protein (hsCRP) levels (r=0.467, p<0.001 and r=0.479, p<0.001, respectively) Conclusions: Our results indicate that iCEB was increased in patients with RA. It is known that high iCEB is associated with torsade de Pointes (TdP) ventricular tachycardia. The increased frequency of ventricular arrhythmias in patients with RA may be TdP-related and can be clarified by the new index of balance between depolarization and repolarization (iCEB).en_US
dc.identifier.doi10.5152/etd.2017.17030
dc.identifier.endpage12en_US
dc.identifier.issn2149-2247
dc.identifier.issn2149-2549
dc.identifier.issue1en_US
dc.identifier.scopus2-s2.0-85046807897en_US
dc.identifier.scopusqualityN/Aen_US
dc.identifier.startpage8en_US
dc.identifier.trdizinid291676en_US
dc.identifier.urihttps://doi.org/10.5152/etd.2017.17030
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/291676
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21778
dc.identifier.volume40en_US
dc.identifier.wosWOS:000432307500003en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherAvesen_US
dc.relation.ispartofErciyes Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectIndex Of Cardioelectrophysiological Balanceen_US
dc.subjectRheumatoid Arthritisen_US
dc.subjectSudden Cardiac Deathen_US
dc.subjectTorsades-De-Pointesen_US
dc.subjectAll-Cause Mortalityen_US
dc.subjectInflammatory Arthritisen_US
dc.subjectCardiovascular-Diseaseen_US
dc.subjectQt-Prolongationen_US
dc.subjectSudden-Deathen_US
dc.subjectRisk-Factoren_US
dc.subjectIntervalen_US
dc.subjectDispersionen_US
dc.subjectRepolarizationen_US
dc.titleEvaluation of Index of Cardioelectrophysiological Balance (iCEB) in Patients with Rheumatoid Arthritisen_US
dc.typeArticleen_US

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