Predicting Lamina Propria Invasion in Patients with Non-muscle-invasive Bladder Cancer: Do RDW and NLR Really Work?

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dc.authoridAydın, Cemil/0000-0002-7271-5748
dc.authoridArda, Ersan/0000-0002-5430-6561
dc.authoridbaykam, mehmet murat/0000-0001-9006-4275
dc.authoridTas, Tuncay/0000-0002-3816-4874
dc.authoridsenturk, aykut bugra/0000-0001-7966-822X
dc.authoridCakiroglu, Basri/0000-0001-5337-5226
dc.authoridEkici, Musa/0000-0002-9155-4126
dc.authorwosidTaş, Tuncay/AAP-3820-2020
dc.authorwosidsenturk, aykut/AAP-6790-2020
dc.authorwosidAydın, Cemil/AAM-2966-2020
dc.authorwosidArda, Ersan/L-7357-2016
dc.authorwosidCakiroglu, Basri/M-5101-2018
dc.contributor.authorSenturk, Aykut Bugra
dc.contributor.authorEkici, Musa
dc.contributor.authorAydin, Cemil
dc.contributor.authorBaykam, Mehmet Murat
dc.contributor.authorTas, Tuncay
dc.contributor.authorArda, Ersan
dc.contributor.authorCakiroglu, Basri
dc.date.accessioned2024-06-12T10:54:48Z
dc.date.available2024-06-12T10:54:48Z
dc.date.issued2019
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: To determine the role of preoperative neutrophil-to-lymphocyte ratio (NLR) and red cell distribution width (RDW) in predicting lamina propria invasion in bladder cancer. Materials and Methods: Eighty-eight patients with non-muscle-invasive bladder cancer were evaluated retrospectively. The patients were divided into those with Ta tumors (group 1: n=36) and those with T1 tumors (group 2: n=52). For each patient, white blood cell, neutrophil, and leukocyte counts and RDW values were evaluated. Results: NLR was significantly lower in patients with Ta tumors. In addition, NLR below 3.22 was associated with 80.6% probability of Ta disease. RDW sensitivity in Ta non-muscle-invasive bladder tumors was much higher compared to T1 tumors. RDW below 15.35 was associated with 94.4% probability of Ta disease. Conclusion: NLR and RDW are basic blood parameters that physicians can assess easily. Our results indicate that a combination of NLR and RDW can help clinicians predict lamina propria invasion in non-muscle-invasive bladder tumors.en_US
dc.identifier.doi10.4274/uob.galenos.2018.1099
dc.identifier.endpage9en_US
dc.identifier.issn2147-2270
dc.identifier.issue1en_US
dc.identifier.startpage6en_US
dc.identifier.trdizinid364249en_US
dc.identifier.urihttps://doi.org/10.4274/uob.galenos.2018.1099
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/364249
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19184
dc.identifier.volume18en_US
dc.identifier.wosWOS:000464095200002en_US
dc.identifier.wosqualityN/Aen_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.language.isoenen_US
dc.publisherGalenos Publ Houseen_US
dc.relation.ispartofUroonkoloji Bulteni-Bulletin Of Urooncologyen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectBladder Canceren_US
dc.subjectSuperficialen_US
dc.subjectLamina Propriaen_US
dc.subjectInvasionen_US
dc.subjectNeutrophil-Lymphocyte Ratioen_US
dc.subjectBlood-Cell Distributionen_US
dc.subjectProgressionen_US
dc.subjectResectionen_US
dc.subjectSurvivalen_US
dc.subjectOutcomesen_US
dc.subjectMarkersen_US
dc.titlePredicting Lamina Propria Invasion in Patients with Non-muscle-invasive Bladder Cancer: Do RDW and NLR Really Work?en_US
dc.typeArticleen_US

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