Template synthesis, characterization, and antimicrobial activity of a new lead (II) Schiff base complex

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dc.authoridTAN ERKOÇ, Nurcihan/0000-0002-0029-0197
dc.authorwosidTAN ERKOÇ, Nurcihan/GQQ-9628-2022
dc.contributor.authorBeynek, Nesrin
dc.contributor.authorTan, Nurcihan
dc.contributor.authorBeynek, Hayrettin
dc.date.accessioned2024-06-12T10:52:00Z
dc.date.available2024-06-12T10:52:00Z
dc.date.issued2015
dc.departmentTrakya Üniversitesien_US
dc.description.abstractA novel lead (II) complex of Schiff base containing three bipyridine units was synthesized by the template reaction between a new amine compound, 6-methyl-6'-(2-aminophenoxymethyl)-2,2'-bipyridine, and 2,2'-bipyridine-6,6'-dicarboxaldehyde in the presence of a Pb(II) perchlorate ion. The new amino compound and Schiff base complex, [PbL](ClO4)(2)center dot 2H(2)O, were characterized by using matrix-assisted laser desorption/ionization with time-of-flight mass spectroscopy, FAR FT-IR, UV/visible spectroscopy, H-1 NMR, elemental analyses (CHN), and molar conductivity measurements. Then the synthesized complex was screened in vitro for its antibacterial and antifungal activities against three Gram-negative and two Gram-positive bacteria and also against Candida albicans as a fungus by the microdilution broth method as a minimal inhibitory concentration. [PbL](ClO4)(2)center dot 2H(2)O exhibits moderate activity on Staphylococcus aureus and Listeria monocytogenes when compared with standard drug and also shows moderate antifungal activity on the fungus Candida albicans.en_US
dc.description.sponsorshipTrakya University [TUBAP-2013/29]en_US
dc.description.sponsorshipThe authors thank the Trakya University for financial support under the research grant no. TUBAP-2013/29.en_US
dc.identifier.doi10.1515/mgmc-2015-0018
dc.identifier.endpage150en_US
dc.identifier.issn0792-1241
dc.identifier.issn2191-0219
dc.identifier.issue5-6en_US
dc.identifier.scopus2-s2.0-84948746156en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage145en_US
dc.identifier.urihttps://doi.org/10.1515/mgmc-2015-0018
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18567
dc.identifier.volume38en_US
dc.identifier.wosWOS:000366524900003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.language.isoenen_US
dc.publisherWalter De Gruyter Gmbhen_US
dc.relation.ispartofMain Group Metal Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectAntimicrobial Activityen_US
dc.subjectLead (II)en_US
dc.subjectSchiff Baseen_US
dc.subjectTemplate Reactionen_US
dc.subjectDonor Macrocyclesen_US
dc.subjectCrystal-Structureen_US
dc.subjectMetal-Ionsen_US
dc.subjectCoordinationen_US
dc.subjectLigandsen_US
dc.titleTemplate synthesis, characterization, and antimicrobial activity of a new lead (II) Schiff base complexen_US
dc.typeArticleen_US

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