Template synthesis, characterization, and antimicrobial activity of a new lead (II) Schiff base complex
Küçük Resim Yok
Tarih
2015
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Walter De Gruyter Gmbh
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
A novel lead (II) complex of Schiff base containing three bipyridine units was synthesized by the template reaction between a new amine compound, 6-methyl-6'-(2-aminophenoxymethyl)-2,2'-bipyridine, and 2,2'-bipyridine-6,6'-dicarboxaldehyde in the presence of a Pb(II) perchlorate ion. The new amino compound and Schiff base complex, [PbL](ClO4)(2)center dot 2H(2)O, were characterized by using matrix-assisted laser desorption/ionization with time-of-flight mass spectroscopy, FAR FT-IR, UV/visible spectroscopy, H-1 NMR, elemental analyses (CHN), and molar conductivity measurements. Then the synthesized complex was screened in vitro for its antibacterial and antifungal activities against three Gram-negative and two Gram-positive bacteria and also against Candida albicans as a fungus by the microdilution broth method as a minimal inhibitory concentration. [PbL](ClO4)(2)center dot 2H(2)O exhibits moderate activity on Staphylococcus aureus and Listeria monocytogenes when compared with standard drug and also shows moderate antifungal activity on the fungus Candida albicans.
Açıklama
Anahtar Kelimeler
Antimicrobial Activity, Lead (II), Schiff Base, Template Reaction, Donor Macrocycles, Crystal-Structure, Metal-Ions, Coordination, Ligands
Kaynak
Main Group Metal Chemistry
WoS Q Değeri
Q4
Scopus Q Değeri
Q3
Cilt
38
Sayı
5-6
