Studies on the synthesis of 3-methyl-6-(substituted-urea/-thiourea)-2(3H)-benzothiazolone derivatives and antimicrobial activities

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dc.authoridOnkol, Tijen/0000-0003-3973-5728
dc.authorwosidONURDAG, Fatma KAYNAK/T-2518-2017
dc.authorwosidOnkol, Tijen/AAA-2377-2021
dc.contributor.authorUnal, Ayse Sibel
dc.contributor.authorOnurdag, Fatma Kaynak
dc.contributor.authorOzgen, Selda
dc.contributor.authorDogruer, Deniz
dc.contributor.authorOnkol, Tijen
dc.date.accessioned2024-06-12T10:50:11Z
dc.date.available2024-06-12T10:50:11Z
dc.date.issued2015
dc.departmentTrakya Üniversitesien_US
dc.description.abstractA series of sixteen new urea and thiourea derivatives at position 6 of 3-methyl-2(3H)-benzothiazolone ring have been prepared and studied using 1R, H-1 NMR, mass spectra and elemental analysis. The urea and thiourea derivatives have been obtained by the reaction of 6-amino-3-methyl-2(3H)-benzothiazolone with appropriate isocyanates and isothiocyanates. The antibacterial, antifungal and antimycobacterial activities of the synthesized compounds have been evaluated in vitro using microdilution and microplate methods.en_US
dc.description.sponsorshipNobel Pharmaen_US
dc.description.sponsorshipThis research was supported by Nobel Pharma.en_US
dc.identifier.endpage259en_US
dc.identifier.issn0376-4699
dc.identifier.issn0019-5103
dc.identifier.issue2en_US
dc.identifier.startpage253en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17894
dc.identifier.volume54en_US
dc.identifier.wosWOS:000351331300005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.language.isoenen_US
dc.publisherNatl Inst Science Communication & Information Resources-Niscairen_US
dc.relation.ispartofIndian Journal Of Chemistry Section B-Organic Chemistry Including Medicinal Chemistryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subject2(3H)-Benzothiazoloneen_US
dc.subjectUreaen_US
dc.subjectThioureaen_US
dc.subjectAntimicrobialen_US
dc.subjectAntitubercular Activityen_US
dc.subjectBiological Evaluationen_US
dc.subjectThioureaen_US
dc.subjectUreaen_US
dc.subjectTuberculosisen_US
dc.subjectResistanceen_US
dc.subjectAgentsen_US
dc.titleStudies on the synthesis of 3-methyl-6-(substituted-urea/-thiourea)-2(3H)-benzothiazolone derivatives and antimicrobial activitiesen_US
dc.typeArticleen_US

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