Studies on the synthesis of 3-methyl-6-(substituted-urea/-thiourea)-2(3H)-benzothiazolone derivatives and antimicrobial activities
Küçük Resim Yok
Tarih
2015
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Natl Inst Science Communication & Information Resources-Niscair
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
A series of sixteen new urea and thiourea derivatives at position 6 of 3-methyl-2(3H)-benzothiazolone ring have been prepared and studied using 1R, H-1 NMR, mass spectra and elemental analysis. The urea and thiourea derivatives have been obtained by the reaction of 6-amino-3-methyl-2(3H)-benzothiazolone with appropriate isocyanates and isothiocyanates. The antibacterial, antifungal and antimycobacterial activities of the synthesized compounds have been evaluated in vitro using microdilution and microplate methods.
Açıklama
Anahtar Kelimeler
2(3H)-Benzothiazolone, Urea, Thiourea, Antimicrobial, Antitubercular Activity, Biological Evaluation, Thiourea, Urea, Tuberculosis, Resistance, Agents
Kaynak
Indian Journal Of Chemistry Section B-Organic Chemistry Including Medicinal Chemistry
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
54
Sayı
2
