Proinflammatory cytokine levels in patients with conversion disorder

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dc.authoridCaliyurt, Okan/0000-0002-0513-0619
dc.authorwosidCaliyurt, Okan/ABE-7339-2020
dc.contributor.authorTiyekli, Utkan
dc.contributor.authorCaliyurt, Okan
dc.contributor.authorTiyekli, Nimet Dilek
dc.date.accessioned2024-06-12T10:58:27Z
dc.date.available2024-06-12T10:58:27Z
dc.date.issued2013
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjective: It was aimed to evaluate the relationship between proinflammatory cytokine levels and conversion disorder both commonly known as stress regulated. Method: Baseline proinflammatory cytokine levels-[Tumour necrosis factor alpha (TNF-alpha), Interleukin-1 beta (IL-1 beta), Interleukin-6 (IL-6)]-were evaluated with enzyme-linked immunosorbent assay in 35 conversion disorder patients and 30 healthy controls. Possible changes in proinflammatory cytokine levels were evaluated again, after their acute phase in conversion disorder patients. Results: Statistically significant decreased serum TNF-alpha levels were obtained in acute phase of conversion disorder. Those levels increased after acute conversion phase. There were no statistically significant difference observed between groups in serum IL-1 beta and (IL-6) levels. Conclusions: Stress associated with conversion disorder may suppress immune function in acute conversion phase and may have diagnostic and therapeutic value.en_US
dc.identifier.doi10.1111/j.1601-5215.2012.00676.x
dc.identifier.endpage143en_US
dc.identifier.issn1601-5215
dc.identifier.issue3en_US
dc.identifier.pmid25287467en_US
dc.identifier.scopus2-s2.0-84879899930en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage137en_US
dc.identifier.urihttps://doi.org/10.1111/j.1601-5215.2012.00676.x
dc.identifier.urihttps://hdl.handle.net/20.500.14551/20075
dc.identifier.volume25en_US
dc.identifier.wosWOS:000320550800003en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherCambridge Univ Pressen_US
dc.relation.ispartofActa Neuropsychiatricaen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectConversion Disorderen_US
dc.subjectCytokineen_US
dc.subjectInterleukin-1 Betaen_US
dc.subjectInterleukin-6en_US
dc.subjectTumour Necrosis Factor Alphaen_US
dc.subjectTumor-Necrosis-Factoren_US
dc.subjectEpstein-Barr-Virusen_US
dc.subjectDissociative Disorderen_US
dc.subjectSomatoform Disordersen_US
dc.subjectStressen_US
dc.subjectImmuneen_US
dc.subjectPsychoneuroimmunologyen_US
dc.subjectBenzodiazepinesen_US
dc.subjectGlucocorticoidsen_US
dc.subjectSensitizationen_US
dc.titleProinflammatory cytokine levels in patients with conversion disorderen_US
dc.typeArticleen_US

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