Proinflammatory cytokine levels in patients with conversion disorder
Küçük Resim Yok
Tarih
2013
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Cambridge Univ Press
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Objective: It was aimed to evaluate the relationship between proinflammatory cytokine levels and conversion disorder both commonly known as stress regulated. Method: Baseline proinflammatory cytokine levels-[Tumour necrosis factor alpha (TNF-alpha), Interleukin-1 beta (IL-1 beta), Interleukin-6 (IL-6)]-were evaluated with enzyme-linked immunosorbent assay in 35 conversion disorder patients and 30 healthy controls. Possible changes in proinflammatory cytokine levels were evaluated again, after their acute phase in conversion disorder patients. Results: Statistically significant decreased serum TNF-alpha levels were obtained in acute phase of conversion disorder. Those levels increased after acute conversion phase. There were no statistically significant difference observed between groups in serum IL-1 beta and (IL-6) levels. Conclusions: Stress associated with conversion disorder may suppress immune function in acute conversion phase and may have diagnostic and therapeutic value.
Açıklama
Anahtar Kelimeler
Conversion Disorder, Cytokine, Interleukin-1 Beta, Interleukin-6, Tumour Necrosis Factor Alpha, Tumor-Necrosis-Factor, Epstein-Barr-Virus, Dissociative Disorder, Somatoform Disorders, Stress, Immune, Psychoneuroimmunology, Benzodiazepines, Glucocorticoids, Sensitization
Kaynak
Acta Neuropsychiatrica
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
25
Sayı
3
