Histopathological and immune alterations in autopsied kidneys

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dc.authoridPuyan, Fulya/0000-0001-5853-0109
dc.authoridOz Puyan, Fulya/0000-0001-5853-0109
dc.authorwosidPuyan, Fulya/V-7074-2019
dc.authorwosiddeng, qiongxia/A-3206-2017
dc.authorwosidOz Puyan, Fulya/A-7077-2018
dc.contributor.authorUsta, Ufuk
dc.contributor.authorTastekin, Ebru
dc.contributor.authorIsler, Erhan
dc.contributor.authorKutlu, Ali K.
dc.contributor.authorPuyan, Fulya Oz
dc.date.accessioned2024-06-12T11:19:01Z
dc.date.available2024-06-12T11:19:01Z
dc.date.issued2014
dc.departmentTrakya Üniversitesien_US
dc.description.abstractObjectives: To collect data on all detectable histologic and immune alterations from the kidneys of 55 autopsy cases. Methods: This prospective study was carried out at the Department of Pathology, Medical Faculty, Trakya University, Edirne, Turkey. Fifty-five cases were subjected to the study among 248 autopsies that were performed in 2011 and 2012. All kidney samples were evaluated under a light microscope and fresh tissue samples were used for immunofluorescence microscopy. Immunohistochemically kappa (kappa) and lambda (lambda) antibodies were applied to the tissue sections. The glomerular, tubulo-interstitial, and vascular alterations, as well as immune depositions were noted. Results: The microscopic morphology was close to normal histology in only 23 cases, and 23 cases had glomerular alterations. Nineteen cases had at least one immune deposition. There was immunoglobulin A deposition in 13 cases, and 9 cases showed positivity for both. and. immunohistochemically, and there was no clonal positivity. Conclusion: The most striking outcome of our study is the high rate of immune depositions. There was also a significant number of glomerular and non-glomerular renal alterations.en_US
dc.description.sponsorshipScientific Research Projects Unit of Trakya University (TUBAP), Erdine, Turkeyen_US
dc.description.sponsorshipAuthors have no conflict of interests, and the work was not supported or funded by any drug company. This study was financially supported by the Scientific Research Projects Unit of Trakya University (TUBAP), Erdine, Turkey.en_US
dc.identifier.endpage1338en_US
dc.identifier.issn0379-5284
dc.identifier.issue11en_US
dc.identifier.pmid25399209en_US
dc.identifier.scopus2-s2.0-84910014567en_US
dc.identifier.scopusqualityQ3en_US
dc.identifier.startpage1331en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/25053
dc.identifier.volume35en_US
dc.identifier.wosWOS:000345911100004en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherSaudi Med Jen_US
dc.relation.ispartofSaudi Medical Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectHepatitis-C Virusen_US
dc.subjectRenal-Diseasesen_US
dc.subjectIga Nephropathyen_US
dc.subjectBiopsyen_US
dc.subjectGlomerulonephritisen_US
dc.subjectClassificationen_US
dc.subjectPopulationen_US
dc.subjectFrequencyen_US
dc.subjectRegistryen_US
dc.subjectRisken_US
dc.titleHistopathological and immune alterations in autopsied kidneysen_US
dc.typeArticleen_US

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