Dirençli diyabetik nöropatik ağrıda puls elektromanyetik alan tedavisinin etkinliği
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Tarih
2010
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info:eu-repo/semantics/openAccess
Özet
Amaç: Diyabetik periferik nöropati, diyabetin en sık görülen ve özürlülüğe neden olan komplikasyonudur. Nöropatik ağrı sıklıkla çoklu farmakolojik tedaviye dirençlidir ve bu ajanların yan etkileri kullanımlarını sınırlar. Nöropatik ağrı tedavisinde farklı alternatif tedaviler araştırılmaktadır. Nonfarmakolojik tedavilerin sistemik yan etkileri düşüktür. Bu rasgele seçilmiş, plasebo kontrollü çalışmada, dirençli diyabetik nöropatik ağrıda puls elektromanyetik alan tedavisinin etkinliği araştırıldı. Hastalar ve Yöntemler: Çalışma, rasgele ayrılan, 25 puls elektromanyetik alan tedavisi (PEMF) ve 25 plasebo grubunda olmak üzere 50 hastayla tamamlandı. Tedavi grubundaki hastaların her iki ayağına on ardışık gün ve günde 1 saat PEMF uygulandı. Olguların tedaviden önce, sonra ve 6. haftadaki kontrollerinde vizüel analog skala ve nöropatik ağrı skala değerlendirmeleri yapıldı. Elektronöromiyografi tetkikleri, tedaviden önce ve 6. hafta kontrollerinde değerlendirildi. Bulgular: Çalışmanın sonucunda, vizüel analog skala ile yapılan ağrı değerlendirmesinde tedavi sonunda %53, kontrol değerlendirmesinde %67 iyileşme saptandı. Nöropatik ağrı skalası farklı verilerinde saptanan düzelme, tedavi grubunda plasebo grubuna göre istatistiksel olarak anlamlıydı. Sinir ileti hızı çalışmalarında iki grup verileri arasında anlamlı istatistiksel fark saptanmadı. Sonuç: Puls elektromanyetik alan tedavisi, ağrı skorları ve polinöropati semptomları üzerindeki olumlu etkileri ile diyabetik nöropatik ağrı tedavisinde alternatif bir seçenek olarak düşünülebilir.
Objectives: Diabetic polyneuropathy is the most common and disabled complication of diabetes mellitus. Pharmacological treatment of diabetic neuropathy is limited because of the side efects of the drugs, used in the treatment of diabetic neuropthy. Alternative treatments are also used in diabetic neuropathy. Systemic side effects of non-pharmacological treatment modalities are rare. We evaluated the value of pulsed electromagnetic field treatment in patients with pain due to diabetic polyneuropathy. Patients and Methods: Symptomatic 95 patients were included in the study, and from these patients, 25 patients were randomized in pulsed electromagnetic field treatment group and 25 patients were randomized in placebo group. Pulsed electromagnetic field device was applied over both feet of the patients for one hour a day (during 10 days). Visual analog scale and neuropathic pain scale of all patients were performed before and after treatment and 6th week. Electroneuromyography was also performed before treatment and 6th week. Results: Improvement of pain determined by visual analog scale was 53% after treatment and 67% six weeks later. The improvement of visual analog scale scores were statistically significant in study group when compared with control subjects. Conclusion: The pulsed electromagnetic field may be an alternative treatment modality in diabetic patients with neuropathic pain.
Objectives: Diabetic polyneuropathy is the most common and disabled complication of diabetes mellitus. Pharmacological treatment of diabetic neuropathy is limited because of the side efects of the drugs, used in the treatment of diabetic neuropthy. Alternative treatments are also used in diabetic neuropathy. Systemic side effects of non-pharmacological treatment modalities are rare. We evaluated the value of pulsed electromagnetic field treatment in patients with pain due to diabetic polyneuropathy. Patients and Methods: Symptomatic 95 patients were included in the study, and from these patients, 25 patients were randomized in pulsed electromagnetic field treatment group and 25 patients were randomized in placebo group. Pulsed electromagnetic field device was applied over both feet of the patients for one hour a day (during 10 days). Visual analog scale and neuropathic pain scale of all patients were performed before and after treatment and 6th week. Electroneuromyography was also performed before treatment and 6th week. Results: Improvement of pain determined by visual analog scale was 53% after treatment and 67% six weeks later. The improvement of visual analog scale scores were statistically significant in study group when compared with control subjects. Conclusion: The pulsed electromagnetic field may be an alternative treatment modality in diabetic patients with neuropathic pain.
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Trakya Üniversitesi Tıp Fakültesi Dergisi
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Cilt
27
Sayı
3
