The effects of the early and ultra-early intervention on the outcome in aneurysmatic subarachnoid hemorrhage

Basit Öğe Kaydı
dc.authoridAkinci, Ahmet Tolgay/0000-0002-9937-076X
dc.authoridSimsek, Osman/0000-0002-8716-5187
dc.authorwosidAkinci, Ahmet Tolgay/S-9731-2017
dc.authorwosidSimsek, Osman/D-4906-2012
dc.contributor.authorAkinci, Ahmet Tolgay
dc.contributor.authorAkturk, Yener
dc.contributor.authorTutunculer, Banu
dc.contributor.authorOrakdogen, Metin
dc.contributor.authorSimsek, Osman
dc.date.accessioned2024-06-12T11:03:58Z
dc.date.available2024-06-12T11:03:58Z
dc.date.issued2021
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBACKGROUND: The optimal timing of intervention for aneurysmatic subarachnoid hemorrhage is one of the historically controversial issues in neurosurgery. Although numerous studies investigated the subject, they had many limitations due to the nature of the disease. Early and ultra-early interventions have gained more and more supporters in recent decades. Nevertheless, the effects of the early and ultra-early intervention on the outcome of the disease are far from clarity. METHODS: A single-center retrospective cohort study was carried out at Trakya University Medical Faculty Training and Practice Hospital. The study includes data on all patients admitted with an aneurysmal subarachnoid hemorrhage between January 1, 2001, and December 31, 2005. Patients were divided into two groups according to their WFNS grade status: Good (I-III) or poor (IV-V) grades. Patients are also classified according to their Glasgow Outcome Scale score: Unfavorable (1-2) or favorable (3-5) outcomes. Data were analyzed statistically, and the effects of the early and ultra-early intervention on the outcome were assessed. RESULTS: A total of 580 patients were admitted in the study period. Among them, 494 were eligible for the study. The median age (interquartile range) was 55 (18) years. While 244 (49.4%) patients were women, 250 (50.6%) patients were men. Three hundred and fourteen (63.6%) patients were operated, and 25 patients (5.1%) were undergone endovascular treatment. The ultra-early intervention was achieved in 60 (12.1%) patients and 142 patients (28.7%, including the previous ultra-early intervention group) early intervention was achieved. A meaningful outcome difference was present between the poor-grade ultra-early treatment group and the rest (p=0.007). Analogously, a meaningful outcome difference was present between the poor-grade early treatment group and the rest (p<0.001). CONCLUSION: This study supports the growing trend toward early or ultra-early intervention in aneurysmatic subarachnoid hemorrhage. Our findings showed that both early and ultra-early interventions have positive effects on the outcome in poor-grade aneurysmatic subarachnoid hemorrhage patients. Future studies with more homogenized and larger samples should be realized to clarify the optimal timing of intervention for aneurysmatic subarachnoid hemorrhage.en_US
dc.identifier.doi10.14744/tjtes.2020.49196
dc.identifier.endpage456en_US
dc.identifier.issn1306-696X
dc.identifier.issue4en_US
dc.identifier.pmid34212997en_US
dc.identifier.scopus2-s2.0-85110263517en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage449en_US
dc.identifier.trdizinid506115en_US
dc.identifier.urihttps://doi.org/10.14744/tjtes.2020.49196
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/506115
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21861
dc.identifier.volume27en_US
dc.identifier.wosWOS:000669548700010en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Assoc Trauma Emergency Surgeryen_US
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal Of Trauma & Emergency Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectIntracranial Aneurysmen_US
dc.subjectOutcomeen_US
dc.subjectSubarachnoid Hemorrhageen_US
dc.subjectTimingen_US
dc.subjectTurkeyen_US
dc.subjectRuptured Intracranial Aneurysmsen_US
dc.subjectSurgeryen_US
dc.subjectManagementen_US
dc.subjectImpacten_US
dc.titleThe effects of the early and ultra-early intervention on the outcome in aneurysmatic subarachnoid hemorrhageen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu
Scopus İndeksli Yayınlar Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu