Relationship between homocysteine and insulin resistance in women with polycystic ovary syndrome

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dc.contributor.authorKilic-Okman, T
dc.contributor.authorGuldiken, S
dc.contributor.authorKucuk, M
dc.date.accessioned2024-06-12T11:03:21Z
dc.date.available2024-06-12T11:03:21Z
dc.date.issued2004
dc.departmentTrakya Üniversitesien_US
dc.description.abstractHyperhomocysteinemia is a risk factor for atherosclerotic vascular diseases. It is known that plasma homocysteine levels are higher in polycystic ovary syndrome (PCOS) patients than in healthy subjects. The aim of our study was to determine the relationship between plasma homocysteine level and insulin resistance in women with PCOS. Twenty-nine patients (age, 23.90 +/- 5.86 years) and twenty-five healthy subjects (age, 25.24 +/- 4.28 years) were involved in the study. Plasma levels of fasting insulin, glucose, homocysteine, FSH, and LH levels were measured. A statistically significant difference in plasma concentrations of HOMA index, homocysteine, basal insulin levels and LH/FSH ratios was observed between groups (P = 0.001, P = 0.001, P = 0.001, and P = 0.01, respectively). There was no relationship between Hey and the other variables. In multiple logistic regression analysis, age, BMI and insulin resistance were not predictors of Hey.en_US
dc.identifier.doi10.1507/endocrj.51.505
dc.identifier.endpage508en_US
dc.identifier.issn0918-8959
dc.identifier.issue5en_US
dc.identifier.pmid15516786en_US
dc.identifier.scopus2-s2.0-8844221283en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage505en_US
dc.identifier.urihttps://doi.org/10.1507/endocrj.51.505
dc.identifier.urihttps://hdl.handle.net/20.500.14551/21622
dc.identifier.volume51en_US
dc.identifier.wosWOS:000225383100011en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherJapan Endocrine Societyen_US
dc.relation.ispartofEndocrine Journalen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectHomocysteineen_US
dc.subjectPolycystic Ovary Syndromeen_US
dc.subjectInsulin Resistanceen_US
dc.subjectIncreased Cardiovascular Risken_US
dc.subjectPlasma Homocysteineen_US
dc.subjectSerum Homocysteineen_US
dc.subjectHeart-Diseaseen_US
dc.subjectHyperinsulinemiaen_US
dc.subjectDeterminantsen_US
dc.subjectHealthyen_US
dc.titleRelationship between homocysteine and insulin resistance in women with polycystic ovary syndromeen_US
dc.typeArticleen_US

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