Relationship between homocysteine and insulin resistance in women with polycystic ovary syndrome
Küçük Resim Yok
Tarih
2004
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Japan Endocrine Society
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Hyperhomocysteinemia is a risk factor for atherosclerotic vascular diseases. It is known that plasma homocysteine levels are higher in polycystic ovary syndrome (PCOS) patients than in healthy subjects. The aim of our study was to determine the relationship between plasma homocysteine level and insulin resistance in women with PCOS. Twenty-nine patients (age, 23.90 +/- 5.86 years) and twenty-five healthy subjects (age, 25.24 +/- 4.28 years) were involved in the study. Plasma levels of fasting insulin, glucose, homocysteine, FSH, and LH levels were measured. A statistically significant difference in plasma concentrations of HOMA index, homocysteine, basal insulin levels and LH/FSH ratios was observed between groups (P = 0.001, P = 0.001, P = 0.001, and P = 0.01, respectively). There was no relationship between Hey and the other variables. In multiple logistic regression analysis, age, BMI and insulin resistance were not predictors of Hey.
Açıklama
Anahtar Kelimeler
Homocysteine, Polycystic Ovary Syndrome, Insulin Resistance, Increased Cardiovascular Risk, Plasma Homocysteine, Serum Homocysteine, Heart-Disease, Hyperinsulinemia, Determinants, Healthy
Kaynak
Endocrine Journal
WoS Q Değeri
Q4
Scopus Q Değeri
Q2
Cilt
51
Sayı
5
