The relationship between FDG PET/CT-defined metabolic parameters and the histopathological subtype of oesophageal carcinomas
Küçük Resim Yok
Tarih
2020
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Int Scientific Information Inc
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Purpose: 18F-fluorodeoxyglucose (F-18-FDG) positron emission tomography (PET) combined with computed tomography (CT) scan is accepted as a standard tool in the staging of oesophageal cancer (OC). Histological subtype of tumour is known to be a major determinant of prognosis and metabolic behaviour. In this study, we aimed to evaluate the effect of histological subtypes of OC on standard uptake value (SUVmax), metabolic tumour volume (MTV), and total lesion glycolysis (TLC) obtained by PET/CT, and also to compare this effect with prognosis. Material and methods: Images and clinical course data of 57 patients who were diagnosed with EC and treated in our hospital between 2009 and 2016 were evaluated in a retrospective manner. PET/CT images were re-analysed in terms of metabolic parameters, and observations were compared with histological subtypes. Results: No significant difference was observed between histological subtypes with SUVmax, overall survival (OS), or progression-free survival (PPS). Thus, MTV was observed to be related with histological subtype; MTV values of adenocancer patients were significantly higher than those of squamous cell cancer patients. Conclusions: Metabolic tumour volume was related with histological subtype of OC, but clinical staging, TLG, and SUVmax values were not related with histological subtype, which may suggest the use of MTV as a routine parameter for OC and inclusion of MTV observations in prognostic scoring.
Açıklama
Anahtar Kelimeler
Oesophageal Cancer, PET/CT, Squamous Cell Cancer, Suvmax, MTV, TLG, Emission Tomography/Computed Tomography, Prognostic Value, Tumor Volume, Stage
Kaynak
Polish Journal Of Radiology
WoS Q Değeri
N/A
Scopus Q Değeri
N/A
Cilt
85
