Increased adiponectin level in non-Hodgkin lymphoma and its relationship with interleukin-10.: Correlation with clinical features and outcome

Basit Öğe Kaydı
dc.contributor.authorPamuk, G. E.
dc.contributor.authorTurgut, B.
dc.contributor.authorDemir, M.
dc.contributor.authorVural, Oe.
dc.date.accessioned2024-06-12T10:50:45Z
dc.date.available2024-06-12T10:50:45Z
dc.date.issued2006
dc.departmentTrakya Üniversitesien_US
dc.description.abstractIt was reported that interieukin-10 (IL-10) level increased in non-Hodgkin lymphoma (NHL) and chronic lymphocytic leukemia (CLL) patients; moreover this was associated with poor prognosis. In addition, it was stated that adiponectin induced the antiinflammatory cytokine IL-10. We evaluated adiponectin and IL-10 levels in NHL and CLL patients. We included newly diagnosed 28 NHL, 23 CLL patients, and 17 healthy subjects. In NHL patients, adiponectin level was higher than in CLL group and controls (p values <0.05). In CLL group, IL-10 level was lower than in NHL, and control groups (p values <0.05). Adiponectin level had a positive correlation with IL-10 level in the NHL patients (r=0.41, p=0.04). In the NHL group, the median survival of patients with high IL-10 levels was shorter (22 months vs. not reached, p=0.03). Increased IL-10 levels helped to predict poor outcome in our NHL patients. High adiponectin levels and a relationship between adiponectin/IL-10 in newly diagnosed NHL patients might suggest a role for both in the immunodysregulation in NHL.en_US
dc.identifier.endpage541en_US
dc.identifier.issn1756-9966
dc.identifier.issue4en_US
dc.identifier.pmid17310845en_US
dc.identifier.startpage537en_US
dc.identifier.urihttps://hdl.handle.net/20.500.14551/18105
dc.identifier.volume25en_US
dc.identifier.wosWOS:000243734200012en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherBmcen_US
dc.relation.ispartofJournal Of Experimental & Clinical Cancer Researchen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAdiponectinen_US
dc.subjectInterleukin-10en_US
dc.subjectNon-Hodgkin Lymphomaen_US
dc.subjectChronic Lymphocytic Leukemiaen_US
dc.subjectPrognosisen_US
dc.subjectClinical Featuresen_US
dc.subjectChronic Lymphocytic-Leukemiaen_US
dc.subjectCellen_US
dc.subjectSerumen_US
dc.subjectIl-10en_US
dc.subjectExpressionen_US
dc.subjectCytokinesen_US
dc.subjectSecreteen_US
dc.subjectDiseaseen_US
dc.titleIncreased adiponectin level in non-Hodgkin lymphoma and its relationship with interleukin-10.: Correlation with clinical features and outcomeen_US
dc.typeArticleen_US

Dosyalar

Koleksiyon

WoS İndeksli Yayınlar Koleksiyonu
PubMed İndeksli Yayınlar Koleksiyonu