Effects of betamethasone on fetoplacental and maternal hemodynamics in preterm pregnancies

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dc.authorwosidSAYIN, N. CENK/A-5801-2018
dc.contributor.authorInan, Cihan
dc.contributor.authorSayin, N. Cenk
dc.contributor.authorDolgun, Zehra N.
dc.contributor.authorErzincan, Selen G.
dc.contributor.authorUzun, Isil
dc.contributor.authorSutcu, Havva
dc.contributor.authorSut, Necdet
dc.date.accessioned2024-06-12T10:54:25Z
dc.date.available2024-06-12T10:54:25Z
dc.date.issued2018
dc.departmentTrakya Üniversitesien_US
dc.description10th National Congress of the Maternal-Fetal-Medicine-and-Perinatology-Society-of-Turkey -- OCT 27-30, 2016 -- Istanbul, TURKEYen_US
dc.description.abstractObjective: To evaluate the possible effects of prenatal steroid administration onDoppler parameters of the umbilical artery, uterine artery, middle cerebral artery, and ductus venosus, the cerebroplacental ratio, and the amniotic fluid index in pretermfetuses. Methods: The present prospective observational study was performed at the Perinatology Department of Trakya University, Edirne, Turkey, between June 1, 2015, and September 1, 2016. It included patients with healthy singleton pregnancies who had received betamethasone at 24-34 weeks of pregnancy. Doppler parameters were measured before (0 hours) and 24, 48, and 72 hours after the administration of betamethasone (two intramuscular doses of 12 mg each, administered 24 hours apart). Results: There were 68 patients included. Pairwise comparisons demonstrated that, at 72 hours after betamethasone administration, the umbilical artery resistance index (P=0.038), the middle cerebral artery systolic/diastolic velocity ratio (P=0.007), and the amniotic fluid index (P=0.017) were reduced, whereas the end-diastolic velocity of the middle cerebral artery was increased (P=0.012), compared with baseline values. Conclusion: Betamethasone had favorable effects on fetal cerebral circulation, with increased end-diastolic velocity in the middle cerebral artery; this could represent a positive effect on cerebral blood circulation and decreased flow resistance in the umbilical artery.en_US
dc.description.sponsorshipMaternal Fetal Med & Perinatol Soc Turkeyen_US
dc.identifier.doi10.1002/ijgo.12478
dc.identifier.endpage359en_US
dc.identifier.issn0020-7292
dc.identifier.issn1879-3479
dc.identifier.issue3en_US
dc.identifier.pmid29493778en_US
dc.identifier.scopus2-s2.0-85044333838en_US
dc.identifier.scopusqualityQ1en_US
dc.identifier.startpage354en_US
dc.identifier.urihttps://doi.org/10.1002/ijgo.12478
dc.identifier.urihttps://hdl.handle.net/20.500.14551/19047
dc.identifier.volume141en_US
dc.identifier.wosWOS:000431652400013en_US
dc.identifier.wosqualityQ3en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherWileyen_US
dc.relation.ispartofInternational Journal Of Gynecology & Obstetricsen_US
dc.relation.publicationcategoryKonferans Öğesi - Uluslararası - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectBetamethasoneen_US
dc.subjectCerebroplacental Ratioen_US
dc.subjectDoppler Ultrasonographyen_US
dc.subjectMiddle Cerebral Arteryen_US
dc.subjectPreterm Birthen_US
dc.subjectUmbilical Arteryen_US
dc.subjectBlood-Flow-Velocityen_US
dc.subjectAntenatal Corticosteroid-Therapyen_US
dc.subjectAmniotic-Fluiden_US
dc.subjectNifedipine Tocolysisen_US
dc.subjectDoppler Velocimetryen_US
dc.subjectWave-Formsen_US
dc.subjectFetalen_US
dc.subjectUterineen_US
dc.subjectLaboren_US
dc.titleEffects of betamethasone on fetoplacental and maternal hemodynamics in preterm pregnanciesen_US
dc.typeConference Objecten_US

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