Speckle-tracking strain assessment of left ventricular dysfunction in synthetic cannabinoid and heroin users
Küçük Resim Yok
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Turkish Soc Cardiology
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Objective: There is growing evidence regarding the numerous adverse effects of synthetic cannabinoids (SCBs) on the cardiovascular system; however, no studies have shown the cardiovascular effects of opioids using strain echocardiography. This study examines the cardiac structure and function using echocardiographic strain imaging in heroin and synthetic cannabinoid users. Methods: This double-blind study included patients who were admitted or referred to a rehabilitation center for heroin (n=31) and synthetic cannabinoid users (n=30). Heroin users and synthetic cannabinoid users were compared with healthy volunteers (n=32) using two-dimensional (2D) speckle-tracking (ST) echocardiography. Results: No differences were found in the baseline characteristics and 2D echocardiography values. The mean global longitudinal strain value was -20.5%+/- 2.4% for SCB users, -22.3%+/- 2.4% for opioid users, and -22.5%+/- 2.2% for healthy volunteers (p=0.024). The mean apical 2-chamber (AP2C) L-strain values were -20.1%+/- 3.1%, -22.4%+/- 3.0%, and -22.3%+/- 2.8% for SCB users, opioid users, and healthy volunteers, respectively (p=0.032). The mean apical 4-chamber (AP4C) L-strain values were -20.7%+/- 2.5% for SCB users, -23.2%+/- 3.2% for opioid users, and -23.8%+/- 3.1% for healthy volunteers (p<0.001). Conclusion: SCBs are potential causes of subclinical left ventricular dysfunction.
Açıklama
Anahtar Kelimeler
Strain, Left Ventricular Function, Synthetic Cannabinoid, Heroin, Myocardial-Infarction, Systolic Function, Receptor, Echocardiography, Disease, Analogs, Cb2
Kaynak
Anatolian Journal Of Cardiology
WoS Q Değeri
Q4
Scopus Q Değeri
Cilt
19
Sayı
6
