The role of urine trypsinogen-2 test in the differential diagnosis of acute pancreatitis in the Emergency Department

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dc.authoridkavalcı, cemil/0000-0003-2529-2946
dc.authoridÖZER, Mehmet/0000-0002-5607-1380
dc.authorwosidkavalcı, cemil/AGG-1308-2022
dc.authorwosidKıyak, Gülten/KBD-1846-2024
dc.authorwosidİriz, Erkan/AAF-2026-2019
dc.authorwosidDAŞ, Murat/GLR-3873-2022
dc.authorwosidÖZER, Mehmet/GQA-5664-2022
dc.contributor.authorCevik, Yunsur
dc.contributor.authorKavalci, Cemil
dc.contributor.authorOzer, Mehmet
dc.contributor.authorDas, Murat
dc.contributor.authorKiyak, Guelten
dc.contributor.authorOzdogan, Mehmet
dc.date.accessioned2024-06-12T10:50:13Z
dc.date.available2024-06-12T10:50:13Z
dc.date.issued2010
dc.departmentTrakya Üniversitesien_US
dc.description.abstractBACKGROUND The aim of the study was to investigate the role and importance of the urine trypsinogen-2 dipstick test in the differential diagnosis of acute pancreatitis in the Emergency Department and to compare results with those of conventional tests. METHODS The study was performed prospectively in the patients admitting to the Emergency Department due to upper abdominal pain. Thirty-two of the 87 patients included in the study had acute pancreatitis diagnosis. Serum amylase, lipase, C-reactive protein (CRP) and urine trypsinogen-2 using Actim pancreatitis dipstick were studied in all patients. The statistical analysis was performed using SPSS 11.5 package program. RESULTS Urine trypsinogen-2 was found positive in 21 (65.6%) of 32 patients. The sensitivity of the test for pancreatitis was identified as 64%, specificity as 85%, positive predictive value as 72%, and negative predictive value as 81%. These values were statistically significant compared to the control group (p<0.01). CONCLUSION Although it has lower sensitivity and specificity compared to amylase and lipase, we suggest that urine trypsinogen-2 test may be an important diagnostic tool in excluding the diagnosis of acute pancreatitis, since it provides results within 5 minutes in the Emergency Department, is cheaper, has a higher negative predictive value, and is easy to use.en_US
dc.identifier.endpage129en_US
dc.identifier.issn1306-696X
dc.identifier.issue2en_US
dc.identifier.pmid20517765en_US
dc.identifier.scopus2-s2.0-77649299392en_US
dc.identifier.scopusqualityQ2en_US
dc.identifier.startpage125en_US
dc.identifier.trdizinid99829en_US
dc.identifier.urihttps://search.trdizin.gov.tr/yayin/detay/99829
dc.identifier.urihttps://hdl.handle.net/20.500.14551/17923
dc.identifier.volume16en_US
dc.identifier.wosWOS:000275822500005en_US
dc.identifier.wosqualityQ4en_US
dc.indekslendigikaynakWeb of Scienceen_US
dc.indekslendigikaynakScopusen_US
dc.indekslendigikaynakTR-Dizinen_US
dc.indekslendigikaynakPubMeden_US
dc.language.isoenen_US
dc.publisherTurkish Assoc Trauma Emergency Surgeryen_US
dc.relation.ispartofUlusal Travma Ve Acil Cerrahi Dergisi-Turkish Journal Of Trauma & Emergency Surgeryen_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.rightsinfo:eu-repo/semantics/closedAccessen_US
dc.subjectAbdominal Painen_US
dc.subjectEmergency Departmenten_US
dc.subjectPancreatitisen_US
dc.subjectUrine Trypsinogen-2en_US
dc.subjectRapid Measurementen_US
dc.subjectDipstick Testen_US
dc.subjectSeverityen_US
dc.subjectEnzymeen_US
dc.titleThe role of urine trypsinogen-2 test in the differential diagnosis of acute pancreatitis in the Emergency Departmenten_US
dc.typeArticleen_US

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